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Superior sagittal sinus thrombosis in a child with nephrotic syndrome

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Abstract

A 3-year-old male with steroid-responsive nephrotic syndrome developed a rare complication, sagittal sinus thrombosis during an episode of gastroenteritis, while on steroid therapy. Anticoagulation, as assessed by partial thromboplastin time, was difficult to maintain, despite administering high doses of heparin, infusions of fresh-frozen plasma to provide antithrombin III, and, subsequently, maximum doses of warfarin (0.3 mg/kg per day). Despite these problems the child made a complete neurological recovery.

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References

  1. Andrassy K, Ritz E, Bommer J (1980) Hypercoagulability in the nephrotic syndrome. Klin Wochenschr 58:1029

    PubMed  Google Scholar 

  2. Mehls O, Andrusy K, Koderisch J, Herzog U, Eberhard R (1987) Hemostasis and thromboembolism in children with nephrotic syndrome. Differences from adults. J Pediatr 110:862

    PubMed  Google Scholar 

  3. Lau SO, Bock GH, Edson JR, Michael AF (1980) Sagittal sinus thrombosis in the nephrotic syndrome. J Pediatr 97:948

    PubMed  Google Scholar 

  4. Casteels K, Demacrel P, Proesmans W (1995) Clinical quiz. Pediatr Nephrol 9:247–249

    PubMed  Google Scholar 

  5. Egli F, Eimigerr P, Stadler G (1974) Thromboembolism in the nephrotic syndrome. Pediatr Res 8:903

    Google Scholar 

  6. Carrie BJ, Salyer WR, Myers BD (1981) Minimal change nephropathy. An electrochemical disorder of the glomerular membrane. Am J Med 70:269

    PubMed  Google Scholar 

  7. Lau SO, Tkachuk JY, Hagegawa DK, Edson JR (1980) Plasminogen and antithrombin III deficiency in the childhood nephrotic syndrome associated with plasminogenuria and antithrombinuria. J Pediatr 96:390

    PubMed  Google Scholar 

  8. O'Reilly RA (1995) Drugs used in the disorders of coagulation. In: Katzung BG (ed) Basic and clinical pharmacology, 6th ed. Appleton and Lange, Connecticut, pp 507–521

    Google Scholar 

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Divekar, A.A., Ali, U.S., Ronghe, M.D. et al. Superior sagittal sinus thrombosis in a child with nephrotic syndrome. Pediatr Nephrol 10, 206–207 (1996). https://doi.org/10.1007/BF00862081

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  • DOI: https://doi.org/10.1007/BF00862081

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