Summary
A variety of anomalies of the central nervous system are observed in trisomy 18. The present case describes an infant having a type II Arnold-Chiari malformation without spina bifida. One previous case of an Arnold-Chiari malformation was reported in trisomy 18 but that infant also had a lumbar meningomyelocoele. Abnormalities of cerebral gyration, hydrocephalus, and agenesis of the corpus callosum were also found in the present case.
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Case, M.E.S., Sarnat, H.B. & Monteleone, P. Type II arnold-chiari malformation with normal spine in trisomy 18. Acta Neuropathol 37, 259–262 (1977). https://doi.org/10.1007/BF00686888
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DOI: https://doi.org/10.1007/BF00686888