Neuroradiology

, Volume 33, Issue 4, pp 305–309

Decreased cerebral glucose metabolism associated with mental deterioration in multi-infarct dementia

  • K. Meguro
  • C. Doi
  • M. Ueda
  • T. Yamaguchi
  • H. Matsui
  • S. Kinomura
  • M. Itoh
  • K. Yamada
  • H. Sasaki
Originals

DOI: 10.1007/BF00587811

Cite this article as:
Meguro, K., Doi, C., Ueda, M. et al. Neuroradiology (1991) 33: 305. doi:10.1007/BF00587811

Summary

Cerebral glucose metabolism of 18 patients with multi-infarct dementia (MID) and 10 age-matched normal subjects were examined with positron emission tomography and the18-F-fluoro-deoxy-glucose technique. MID patients had significantly lower glucose metabolism in all the grey matter regions measured and were also characterized by more individuality in metabolic pattern. MID patients were also evaluated as to intelligence quotient (IQ). A positive correlation between IQ as shown by the Tanaka-Binet test and glucose metabolism for the entire grey matter was found. The clinical applicability of this test for predicting cerebral metabolism is discussed.

Key words

Senile dementiaMulti-infarct dementiaIntelligence quotientGlucose metabolismPositron emission tomography

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • K. Meguro
    • 1
    • 2
  • C. Doi
    • 3
  • M. Ueda
    • 2
  • T. Yamaguchi
    • 1
  • H. Matsui
    • 4
  • S. Kinomura
    • 2
    • 4
  • M. Itoh
    • 5
  • K. Yamada
    • 4
  • H. Sasaki
    • 1
  1. 1.Department of Geriatric MedicineTohoku University School of MedicineSendaiJapan
  2. 2.Miyama HospitalSendaiJapan
  3. 3.Department of PsychologyTohoku University School of LiteratureSendaiJapan
  4. 4.Department of Radiology and Nuclear Medicine, The Research Institute for Tuberculosis and CancerTohoku UniversitySendaiJapan
  5. 5.Cyclotron Radioisotope CenterTohoku University School of MedicineSendaiJapan