Abstract
8-Amino-7-theophyllylacetic acids and their esters were obtained by reaction of 8-amino(alkylamino, arylamino)theophyllines with haloacetic acids and their esters. The structures of the products were established, and the conditions for cyclization to imidazolino[1,2-f]xanthin-2-one derivatives were studied. The corresponding methylene-group-substituted derivatives were synthesized by reaction of the imidazolino[1,2-f]xanthin-2-one derivatives with aldehydes, isatin, aromatic nitroso compounds, and arenediazonium salts. The ylidene derivatives of this threering system were also obtained by reaction of 8-amino-7-theophyllylacetic acids or their esters with carbonyl compounds.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1132–1135, August, 1976.
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Nosachenko, V.I., Kochergin, P.M. & Steblyuk, P.N. Synthesis of imidazolino [1,2-f]xanthin-2-ones and their methylene-group-substituted derivatives. Chem Heterocycl Compd 12, 935–938 (1976). https://doi.org/10.1007/BF00510120
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DOI: https://doi.org/10.1007/BF00510120