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Pyridinium salts

III. Alkylation of 2-(pyridin-2-yl)benzazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 2-(pyridin-2-yl)benzoxazole and 2-(pyridin-2-yl)benzothiazole with methyl iodide forms the corresponding pyridinium salts. In the case of 2-(pyridin-2-yl)benzimidazole, the imidazole ring is quaternized first, and only then the pyridine ring. The catalytic hydrogenation of 2-(benzoxazol-2-yl)-1-methylpyridinium salts gives 2-(1-methylpiperidin-2-yl)benzoxazole.

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Literature cited

  1. P. P. Zarin, É. S. Lavrinoyich, and A. K. Aren, Khim. Geterotsikl. Soedin., 108 (1974).

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For Communication II, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 112–114, January, 1974.

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Zarin', P.P., Lavrinovich, É.S. & Aren, A.K. Pyridinium salts. Chem Heterocycl Compd 10, 99–101 (1974). https://doi.org/10.1007/BF00475920

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  • DOI: https://doi.org/10.1007/BF00475920

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