Chemistry of Heterocyclic Compounds

, Volume 10, Issue 1, pp 99–101

Pyridinium salts

III. Alkylation of 2-(pyridin-2-yl)benzazoles
  • P. P. Zarin'
  • É. S. Lavrinovich
  • A. K. Aren
Article

DOI: 10.1007/BF00475920

Cite this article as:
Zarin', P.P., Lavrinovich, É.S. & Aren, A.K. Chem Heterocycl Compd (1974) 10: 99. doi:10.1007/BF00475920

Abstract

The reaction of 2-(pyridin-2-yl)benzoxazole and 2-(pyridin-2-yl)benzothiazole with methyl iodide forms the corresponding pyridinium salts. In the case of 2-(pyridin-2-yl)benzimidazole, the imidazole ring is quaternized first, and only then the pyridine ring. The catalytic hydrogenation of 2-(benzoxazol-2-yl)-1-methylpyridinium salts gives 2-(1-methylpiperidin-2-yl)benzoxazole.

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • P. P. Zarin'
    • 1
  • É. S. Lavrinovich
    • 1
  • A. K. Aren
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga