Skip to main content
SpringerLink
Log in

Pigmented villonodular synovitis

  • Original Articles
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Summary

Pigmented villonodular synovitis is a benign disease of the synovial membrane of joints, tendon sheaths, or bursae, which nevertheless can cause marked local destruction. Its diagnosis is often delayed because complaints and symptoms are nonspecific. Familiarity with the disease may ensure an earlier diagnosis and consequently early onset of therapy, which may prevent serious damage. This paper describes 18 patients suffering from localized or diffuse pigmented villonodular synovitis. Findings possibly suggestive of pigmented villonodular synovitis include hemarthrosis, soft tissue swelling, radiological evidence of cyst formation at a distance from the weight-bearing area of a joint, an increased triglyceride concentration, and a positive bone scan. A normal appearance on arthroscopy does not rule out the disease. Therapeutic results are better in the localized than in the diffuse form of the disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Andersen JA, Ladefoged C (1988) A case of aggressive pigmented villonodular synovitis. Acta Orthop Scand 59:467–470

    Google Scholar 

  2. Atmore WG, Dahlin DC, Ghormley RK (1956) Pigmented villonodular synovitis. A clinical and pathologic study. Minn Med 39:196–202

    Google Scholar 

  3. Breimer CW, Freiberger RH (1958) Bone lesions associated with villonodular synovitis. Am J Roentgenol 79:618–629

    Google Scholar 

  4. Byers PD, Cotton RE, Deacon OW, Lowry M, Newman PH, Sissons HA, Thomson AD (1968) The diagnosis and treatment of pigmented villonodular synovitis. J Bone Joint Surg [Br] 50:290–305

    Google Scholar 

  5. Chung SMK, Janes JM (1965) Diffuse pigmented villonodular synovitis of the hip joint. J Bone Joint Surg [Am] 47:293–303

    Google Scholar 

  6. Danzig LA, Gershuni DH, Resnick D (1982) Diagnosis and treatment of diffuse pigmented villonodular synovitis of the hip. Clin Orthop Rel Res 168:42–47

    Google Scholar 

  7. Dorfmann H (1985) Arthroscopic detection of synovial disorders. Contemp Orthop 10:19–29

    Google Scholar 

  8. Dorwart RH, Genant HK, Johnston WH, Morris JM (1984) Pigmented villonodular synovitis of synovial joints: clinical, pathologic and radiologic features. Am J Radiol 143:887–885

    Google Scholar 

  9. Flandry FC, Jacobsen KE, Andrews JR (1986) Localized pigmented villonodular synovitis of the knee mimicking meniscal injury. Arthroscopy 2:217–221

    Google Scholar 

  10. Flandry FC, Hughston JC (1987) Current concepts review: pigmented villonodular synovitis. J Bone Joint Surg [Am] 69:942–949

    Google Scholar 

  11. Goldman AB, DiCarlo EF (1988) Pigmented villonodular synovitis. Diagnosis and differential diagnosis. Radiol Clin North Am 26:1327–1347

    Google Scholar 

  12. Granowitz SP, Mankin HJ (1967) Localized pigmented villonodular synovitis of the knee. Report of five cases. J Bone Joint Surg [Am] 49:122–128

    Google Scholar 

  13. Granowitz SP, D'Antonio J, Mankin HL (1976) The pathogenesis and long-term end results of pigmented villonodular synovitis. Clin Orthop 114:335–351

    Google Scholar 

  14. Hirohata K (1968) Light and electron microscopic studies of individual cells in pigmented villonodular synovitis and bursitis. Kobe J Med Sci 14:251–279

    Google Scholar 

  15. Jaffe HL, Lichtenstein L, Sutro CJ (1941) Pigmented villonodular synovitis, bursitis and tenosynovitis. Arch Pathol 31:731–765

    Google Scholar 

  16. Jergesen HE, Mankin HJ, Schiller AL (1978) Diffuse pigmented villonodular synovitis of the knee mimicking primary bone neoplasm. J Bone Joint Surg [Am] 60:825–829

    Google Scholar 

  17. Johansson JE, Ajjoub S, Coughlin LP, Wener JA, Cruess RL (1982) Pigmented villonodular synovitis of joints. Clin Orthop Rel Res 163:159–166

    Google Scholar 

  18. Kottal RA, Vogler JB, Matamoros A, Alexander AH, Cookson JL (1987) Pigmented villonodular synovitis: a report of MR imaging in two cases. Radiology 163:551–553

    Google Scholar 

  19. Larmon WA (1965) Pigmented villonodular synovitis. Med Clin North Am 49:141–150

    Google Scholar 

  20. McMaster PE (1960) Pigmented villonodular synovitis with invasion of bone. Report of six cases. J Bone Joint surg [Am] 42:1170–1183

    Google Scholar 

  21. Myers BW, Masi AT, Feigenbaum SL (1980) Pigmented villonodular synovitis and tenosynovitis. A clinical epidemiologic study of 166 cases and literature review. Medicine 59:223–238

    Google Scholar 

  22. Nilsonne U, Moberger G (1969) Pigmented villonodular synovitis of joints. Histological and clinical problems in diagnosis. Acta Orthop Scand 40:448–460

    Google Scholar 

  23. Rao AS, Vigorita VJ (1984) Pigmented villonodular synovitis. J Bone Joint Surg [Am] 66:76–94

    Google Scholar 

  24. Scott PM (1968) Bone lesions in pigmented villonodular synovitis. J Bone Joint Surg [Br] 50:306–311

    Google Scholar 

  25. Smith JH, Pugh DG (1962) Roentgenographic aspects of articular pigmented villonodular synovitis. Am J Roentgenol 87:1146–1156

    Google Scholar 

  26. Weisz GM, Gal A, Kitchener PN (1988) Magnetic resonance imaging in the diagnosis of aggressive villonodular synovitis. Clin Orthop 236:303–306

    Google Scholar 

  27. Wiss DA (1982) Recurrent villonodular synovitis of the knee. Successful treatment with yttrium-90. Clin Orthop Rel Res 169:139–144

    Google Scholar 

  28. Young JM, Hudacek AG (1954) Experimental production of pigmented villonodular synovitis in dogs. Am J Pathol 30:799–811

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthopedics, Groningen University Hospital, Groningen, The Netherlands

    J. Klompmaker,  R. P. H. Veth & H. K. L. Nielsen

  2. Department of Plastic Surgery, Groningen University Hospital, Groningen, The Netherlands

    P. H. Robinson

  3. Department of Pathological Anatomy, Groningen University Hospital, Groningen, The Netherlands

    W. M. Molenaar

Authors
  1. J. Klompmaker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. P. H. Veth
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. H. Robinson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. W. M. Molenaar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. K. L. Nielsen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Klompmaker, J., Veth, R.P.H., Robinson, P.H. et al. Pigmented villonodular synovitis. Arch Orthop Trauma Surg 109, 205–210 (1990). https://doi.org/10.1007/BF00453142

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00453142

Keywords

Search

Navigation