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References
Amar, L.C., Dandolo, L., Hanauer, A., Ryder Cook, A., Arnaud, D., Mandel, J.-L., Avner, P. (1988) Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse. Genomics 2, 220–230.
Bishop, D.T. (1985) The information content of phase-known matings for ordering genetic loci. Genet. Epidemiol. 2, 349–361.
Conley, M.E., Burks, A.W., Herrod, H.G., Puck, J.M. (1991). Molecular analysis of X-linked agammaglobulinemia with growth hormone deficiency. J. Pediatr. 119, 392–397.
Davisson, M.T., Lalley, P.A., Peters, J., Doolittle, D.P., Hillyard, A.L., Searle, A.G. (1991). Report of the comparative committee for human, mouse and other rodents. Cytogenet. Cell Genet. 58, 1152–1189.
Dietrich, W., Katz, H., Lincoln, S.E., Shin, H.S., Friedman, J., Dracopoli, N.C., Lander, E.S. (1992). A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131, 423–447.
Eicher, E.M., Lee, B.K., Washburn, L.L., Hale, D.W., King, T.R. (1992). Telomere-related markers for the pseudoautosomal region of the mouse genome. Proc. Natl. Acad. Sci. USA 89, 2160–2164.
Finney, M., Ruvkun, G., Horvitz, R.H. (1988) The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors. Cell 55, 757–769.
Green, E.L. (1981). Linkage recombination and mapping. In Genetics and Probability in Animal Breeding Experiments, E. Green, ed. (New York: MacMillan), pp. 77–113.
Hara, Y., Rovescalli, A.C., Kim, Y., Nirenberg, M. (1992). Structure and evolution of four POU domain genes expressed in mouse brain. Proc. Natl. Acad. Sci. USA 89, 3280–3284.
He, X., Treacy, M.N., Simmons, D.M., Ingraham, H.A., Swanson, L.W., Rosenfeld, M.G. (1989). Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature 340, 35–42.
Herr, W., Sturm, R.A., Clerc, R.G., Corcoran, L.M., Baltimore, D., Sharp, P.A., Ingraham, H.A., Rosenfeld, M.G., Finney, M., Ruvkun, G., Horvitz, H.R. (1988). The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2 and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2, 1513–1516.
Hochschild, A., Irwin, N., Ptashne, M. (1983). Repressor structure and the mechanism of positive control. Cell 32, 319–325.
Keppen, L.D., Leppert, M.F., O'Connell, P., Nakamura, Y., Stauffer, D., Lathrop, M., Lalovel, J.-M., White, R. (1987). Etiological heterogeneity in X-linked spastic paraplegia. Am. J. Hum. Genet. 41, 933–943.
Kuhn, R., Monuki, E.S., Lemke, G. (1991). The gene encoding the transcription factor SCIP has features of an expressed retroposon. Mol. Cell. Biol. 11, 4642–4650.
Le Moine, C., Young, W.S. III (1992). RHS2, a POU domain-containing gene, and its expression in developing and adult rat. Proc. Natl. Acad. Sci. USA 89, 3285–3289.
Li, S., Crenshaw, B.E. III, Rawson, E.J., Simmons, D.M., Swanson, L.W., Rosenfeld, M.G. (1990). Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene Pit-1. Nature 347, 528–533.
Mathis, J.M., Simmons, D.M., He, X., Swanson, L.W., Rosenfeld, M.G. (1992). Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 11, 2551–2561.
O'Brien, S.J., Marshall Graves, J.A. (1991). Report of the committee on comparative gene mapping. Cytogenet. Cell Genet. 58, 1124–1151.
Okamoto, K., Wakamiya, M., Noji, S., Koyoma, E., Taniguchi, S., Takemura, R., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Muramatsu, M., Hamada, H. (1993). A novel class of murine POU gene predominantly expressed in central nervous system. J. Biol. Chem. 268, 7449–7457.
Pfäffle, R.W., DiMattia, G.E., Parks, J.S., Brown, M.R., Wit, J.M., Jansen, M., Van der Nat, H., Van den Brande, J.L., Rosenfeld, M.G., Ingraham, H.A. (1992). Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia. Science 257, 1118–1121.
Phelan, P.D., Connelly, J., Martin, F.I.R., Wetenhall, H.N. (1971). X-linked recessive hypopituitarism. Birth Defects VII(6), 24–27.
Radovick, S., Nations, M., Du, Y., Berg, L.A., Weintraub, B.D., Wondisford, F.E. (1992). A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency. Science 257, 1115–1118.
Rosenfeld, M.G. (1992). POU-domain transcription factors: pou-er-ful developmental regulators. Genes Dev 5, 897–907.
Schaffner, W. (1989). How do different transcription factors binding to the same DNA sequence sort out their jobs? Trends Genet. 5, 37–39.
Schimke, R.N., Spaulding, J.J., Hollowell, J.G. (1971). X-linked congenital panhypopituitarism. Birth Defects VII(6), 21–23.
Thomas, J.D., Sideras, P., Edvard Smith, C.I., Vorechovsky, I., Chapman, V., Paul, W.E. (1993). Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science 261, 355–361.
Vetrie, D., Vorechovsky, I., Sideras, P., Holland, J., Davies, A., Flinter, F., Hammarström, L., Kinnon, C., Levinsky, R., Bobrow, M., Edvard Smith, C.I., Bentley, D.R. (1993). The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature 361, 226–233.
Willard, H.F., Riordan J.R. (1985). Assignment of the gene for myelin proteolipid protein to the X chromosome: implications for X-linked myelin disorders. Science 230, 940–942.
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Douville, P.J., Atanasoski, S., Tobler, A. et al. The brain-specific POU-box gene Brn4 is a sex-linked transcription factor located on the human and mouse X Chromosomes. Mammalian Genome 5, 180–182 (1994). https://doi.org/10.1007/BF00352353
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DOI: https://doi.org/10.1007/BF00352353