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Development of Dickie's small eye: An early lethal mutation in the house mouse

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Summary

Mice heterozygous for Dickie's small eye (Dey) are small and have malformed eyes (Theiler et al. 1978). The development of homozygous Dey/Dey was more difficult to analyze than heterozygous Dey/+. This investigation attempted to identify the homozygotes and to distinguish them from Dey/+ and +/+ resorptions. Such a distinction was possible only when enough specimens were available. The mutants are poor breeders and the collection of the necessary material has taken several years.

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Authors and Affiliations

  1. Anatomisches Institut der Universität Gloriastr. 19, CH-8006, Zurich, Schweiz

    Karl Theiler

  2. The Jackson Laboratory, 04609, Bar Harbor, Maine, USA

    Don S. Varnum & Leroy C. Stevens

Authors
  1. Karl Theiler
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  2. Don S. Varnum
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  3. Leroy C. Stevens
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Additional information

This work was supported by Research Grant CA 02662 from the National Cancer Institute

The Jackson Laboratory is fully accredited by the American Association for Accreditation of Laboratory Animal Care

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Theiler, K., Varnum, D.S. & Stevens, L.C. Development of Dickie's small eye: An early lethal mutation in the house mouse. Anat Embryol 161, 115–120 (1980). https://doi.org/10.1007/BF00304672

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  • DOI: https://doi.org/10.1007/BF00304672

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