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Angiotropic lymphoma (malignant angioendotheliomatosis) presenting with rapidly progressive dementia

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Summary

An 87-year-old male presented with rapidly progressive dementia, disorder of consciousness and myoclonus, suggesting Creutzfeldt-Jakob disease, but with nonspecific EEG and negative CT findings. Autopsy revealed a malignant angiotropic lymphoma with accumulation of tumor cells within small vessels of the brain and visceral organs. Immunohistochemistry disclosed a large cell lymphoma of B cell type.

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Authors and Affiliations

  1. Pathologisch-bakteriologisches Institut, Psychiatrisches Krankenhaus, Baumagatner Höhe 1, A-1145, Wien, Austria

    M. Drlicek & U. Liszka

  2. Ludwig Boltzmann Institut für klinische Neurobiologie, Baumgartner, Höhe 1, A-1145, Wien, Austria

    M. Drlicek, W. Grisold & U. Liszka

  3. Neurologische Abteilung, Kaiser Franz Josef Spital, Kundratstrasse 3, A-1100, Wien, Austria

    W. Grisold & P. Hitzenberger

  4. Pathologisch-bakteriologisches Institut, Kaiser Franz Josef Spital, Kundratstrasse 3, A-1100, Wien, Austria

    E. Machacek

Authors
  1. M. Drlicek
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  2. W. Grisold
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  3. U. Liszka
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  4. P. Hitzenberger
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  5. E. Machacek
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Drlicek, M., Grisold, W., Liszka, U. et al. Angiotropic lymphoma (malignant angioendotheliomatosis) presenting with rapidly progressive dementia. Acta Neuropathol 82, 533–535 (1991). https://doi.org/10.1007/BF00293391

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  • DOI: https://doi.org/10.1007/BF00293391

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