Cancer Chemotherapy and Pharmacology

, Volume 23, Issue 5, pp 329–330

Severe renal failure following high-dose ifosfamide and mesna

Authors

  • Pax H. B. Willemse
    • Department of Internal Medicine, Division of Medical OncologyUniversity Hospital
  • Paul E. de Jong
    • Department of NephrologyUniversity Hospital
  • Job B. Elema
    • Department of PathologyUniversity Hospital
  • Nanno H. Mulder
    • Department of Internal Medicine, Division of Medical OncologyUniversity Hospital
Original Articles Ifosfamide, Renal Function, Mesna

DOI: 10.1007/BF00292414

Cite this article as:
Willemse, P.H.B., de Jong, P.E., Elema, J.B. et al. Cancer Chemother. Pharmacol. (1989) 23: 329. doi:10.1007/BF00292414

Summary

A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion. Biopsy findings, the possible underlying mechanism, and the existing literature are discussed.

Copyright information

© Springer-Verlag 1989