Severe renal failure following high-dose ifosfamide and mesna
- Cite this article as:
- Willemse, P.H.B., de Jong, P.E., Elema, J.B. et al. Cancer Chemother. Pharmacol. (1989) 23: 329. doi:10.1007/BF00292414
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A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion. Biopsy findings, the possible underlying mechanism, and the existing literature are discussed.