Summary
A theorem of Tikhonov yields the mathematical justification for the steady-state approximation which is frequently used in biochemical kinetics. In this paper we derive a set of expressions for this approximation which are well suited for the automatical evaluation by a computer. But they may be used for the investigation of simple kinetic schemes by algebraic methods, too.
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Göbber, F., Seelig, F.F. Conditions for the application of the steady-state approximation to systems of differential equations. J. Math. Biology 2, 79–86 (1975). https://doi.org/10.1007/BF00276018
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DOI: https://doi.org/10.1007/BF00276018