Skip to main content
Log in

Radiation absorbed dose estimates to the embryo from some nuclear medicine procedures

  • Published:
European Journal of Nuclear Medicine Aims and scope Submit manuscript

Abstract

Using the specific absorbed fractions reported by Smith and Warner, the radiation doses absorbed by the embryo in early pregnancy were calculated for various radiopharmaceuticals used in the diagnostic procedures of nuclear medicine. Radiopharmaceuticals are considered which are excreted predominantly through urine and cause the doses to the embryo to be 40%–90% higher than gonad doses. Also discussed are large differences of doses reported by various authors to the embryo by 99mTcpertechnetate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Cloutier, R.J., Watson, E., Snyder, W.S.: Dose to the fetus during the first three months from gamma sources in maternal organs. In: Radiopharmaceutical Dosimetry symposium. Proc. Symp. Oak Ridge, HEW Publication (FDA) 76-8044. Rockville: U.S. Department of Health Education and Welfare 1976

    Google Scholar 

  • Dillman, L.T., von der Lage, F.C.: Radionuclide decay schemes and nuclear parameters for use in radiation dose estimation. MIRD Pamphlet No. 10. New York: Society of Nuclear Medicine 1975

    Google Scholar 

  • Ellis, R.E., Nordin, B.E.C., Tothill, P., Veall, N.: The application of the ‘ten-day rule’ in radiopharmaceutical investigations. Br. J. Radiol. 50, 200–202 (1977)

    Google Scholar 

  • Hahn, K., Brod, K.H., Wolf, R., Eissner, D.: Untersuchungen zur Strahlenbelastung des Feten bei nuklearmedizinischen Untersuchungen von Graviden. In: Nuklearmedizin. Qualitätskriterien in der Nuklearmedizin. Stuttgart-New York: F.K. Schattauer 1977

    Google Scholar 

  • Hahn, K., Wolf, R., Eissner, D.: Die Strahlenbelastung des Foeten bei nuklearmedizinischen Untersuchungen von Graviden. Vortrag beim Inter. Röntgenkongress, Rio de Janeiro 1978

  • ICRP Publication 25: The handling, storage and disposal of nonsealed radionculides in hospitals and medical research establishments. Annals of the ICRP 1, No. 2 (1977)

  • Lathrop, K.A., Gloria, I.V., Harper, P.V.: Response of mouse foetus to radiation from Na 99mTcO4. In: Biological and Environmental effects of low-level radiation. Proc. Symp. Chicago, Vol. II, pp. 211–221. Vienna: IAEA 1976

    Google Scholar 

  • Lathrop, K.A., Johnston, R.E., Blau, M., Rotschild, E.O.: Radiation dose to humans from 75Se-L-selenomethionine. J. Nucl. Med. 13, Suppl. No. 6 (1972)

  • Mahon, D.F., Subramanian, G., McAfee, J.G.: Experimental comparison of radioactive agents for studies of the placenta. J. Nucl. Med. 14, 651–659 (1973)

    Google Scholar 

  • McEwan, A.C.: Patient radiation doses from radiopharmaceuticals. Report NRL 1974/3. Chritchurch: National Radiation Laboratory 1974

    Google Scholar 

  • Mian, T.A., Suzuki, H.J., Haynie, T.P., Meistrich, M.L.: Radiation damage to mouse testis cells from 99mTc-pertechnetate. J. Nucl. Med. 18, 1116–1122 (1977)

    Google Scholar 

  • MIRD/Dose estimate report No. 2. Summary of current radiation dose estimates to humans from 66Ga-, 67Ga-, 68Ga-, and 72Ga-citrate. J. Nucl. Med. 14, 755–756 (1977)

  • MIRD/Dose estimate report No. 5. Summary of current radiation dose estimates to humans from 123I, 124I, 125I, 126I, 130I, 131I and 132I as sodium iodide. J. Nucl. Med. 16, 857–860 (1975)

    Google Scholar 

  • MIRD/Dose estimate Report No. 8. Summary of current radiation dose estimates to normal humans from 99mTc as sodium pertechnetate. J. Nucl. Med. 17, 74–77 (1976)

    Google Scholar 

  • Roedler, H.D., Kaul, A.: Radiation absorbed dose from medically administered radiopharmaceuticals. In: Biomedical dosimetry. Proc. Symp. Vienna, pp. 655–665. Vienna: IAEA 1975

    Google Scholar 

  • Sear, R.: Radioisotopes and the ‘10-day rule’. Br. J. Radiol. 47, 822 (1974)

    Google Scholar 

  • Smith, E.M., Warner, G.G.: Estimates of radiation dose to the embryo from nuclear medicine procedures. J. Nucl. Med. 17, 836–839 (1976)

    Google Scholar 

  • Subramanian, G., McAfee, J.G., Blair, R.J., Kallfelz, F.A., Thomas, F.D.: Technetium-99m-methylene disphosphonate — a superior agent for skeletal imaging: comparison with other technetium complexes. J. Nucl. Med. 16, 744–755 (1975)

    Google Scholar 

  • The developing role of short-lived radionuclides in nuclear medicine. HEW Publication (FDA) 77-8035. Rockville: U.S. Department of Health, Education and Welfare 1977

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hušák, V., Wiedermann, M. Radiation absorbed dose estimates to the embryo from some nuclear medicine procedures. Eur J Nucl Med 5, 205–207 (1980). https://doi.org/10.1007/BF00271900

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00271900

Keywords

Navigation