Applied Microbiology and Biotechnology

, Volume 28, Issue 4, pp 324–329

Transformations of acetates of citronellol, geraniol, and linalool by Aspergillus niger: regiospecific hydroxylation of citronellol by a cell-free system

  • K. Madhava Madyastha
  • N. S. R. Krishna Murthy
Biotechnology

DOI: 10.1007/BF00268189

Cite this article as:
Madyastha, K.M. & Murthy, N.S.R.K. Appl Microbiol Biotechnol (1988) 28: 324. doi:10.1007/BF00268189

Summary

Incubation of acetates of geraniol, citronellol and linalool with Aspergillus niger resulted in their hydrolysis to corresponding alcohols which were further hydroxylated to their respective 8-hydroxy derivatives. In the case of linalyl acetate, besides linalool and 8-hydroxylinalool, small amounts of geraniol and α-terpineol were also formed. Microsomes (105 000xg sediment) prepared from induced cells of A. niger were found to convert (1-3H)citronellol to 8-hydroxy citronellol in the presence of NADPH and O2. The pH optimum for the hydroxylase was found to be 7.6.

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • K. Madhava Madyastha
    • 1
  • N. S. R. Krishna Murthy
    • 1
  1. 1.Bio-Organic Section, Department of Organic ChemistryIndian Institute of ScienceBangaloreIndia