European Journal of Nuclear Medicine

, Volume 3, Issue 2, pp 87–89


A contribution to the study of its structure
  • Ugo Fonda
  • Bente Pedersen

DOI: 10.1007/BF00251629

Cite this article as:
Fonda, U. & Pedersen, B. Eur J Nucl Med (1978) 3: 87. doi:10.1007/BF00251629


Sephadex column chromatography has shown that 99mTc-diethyl-HIDA consists of two clearly separable components. One of them seems to be an intermediate compound changing into the other, almost completely within two hours after reconstitution of the diethyl-HIDA (Solco HIDA) with pertechnetate. The two components could be the mono- and biscomplex of N-(2,6-diethyl-acetanilid)-imino diacetic acid with one atom of technetium. Animal experiments show that there is no important difference in the biological distribution in mice between the two components.

Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • Ugo Fonda
    • 1
  • Bente Pedersen
    • 1
  1. 1.The Isotope-PharmacyBrønshøjDenmark
  2. 2.Klinika Za Nuklearno Medicino-Klinični CenterLjubljanaYugoslavia