Article

Journal of Neuro-Oncology

, Volume 3, Issue 4, pp 315-321

T1 and T2 Proton Nuclear Magnetic Resonance (N.M.R.) relaxation times in vitro and human intracranial tumours

Results from 98 patients
  • M ChatellAffiliated withLaboratoire de Neuropathologie, Centre Hospitalier Universitaire
  • , F DarcelAffiliated withLaboratoire de Neuropathologie, Centre Hospitalier Universitaire
  • , J de CertainesAffiliated withLaboratoire de RMN Médicale, Faculté de Médecine
  • , L BenoistAffiliated withLaboratoire de RMN Médicale, Faculté de Médecine
  • , AM BernardAffiliated withLaboratoire de RMN Médicale, Faculté de Médecine

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Summary

137 samples of intracranial tumours have been studied in proton NMR spectroscopy. T1 and T2 relaxation times are above those of normal grey and white matter. Differential diagnosis between benign and malignant brain tumours does not seem feasible upon proton T1 and T2 alone. Histological correlations allowed us to specify secondary changes accounting for T1 and T2 variations (oedema, microcyst, stroma reaction, necrosis).

Keywords

brain tumours gliomas proton NMR