Skip to main content
SpringerLink
Log in

Color pattern-reversal visual evoked potential in eyes with ocular hypertension and primary open-angle glaucoma

  • Published:
Documenta Ophthalmologica Aims and scope Submit manuscript

Abstract

Color pattern-reversal visual evoked potential testing was performed in 99 normal eyes, 27 eyes with ocular hypertension and 30 eyes with primary open-angle glaucoma with the use of black-white, black-red and black-blue color checkerboard stimuli. The PI wave peak time and amplitude of the eyes with ocular hypertension and glaucoma were significantly different from those of age-similar normal eyes, especially on the black-red and black-blue checkerboards (p < 0.001). The differences between the ocular hypertensive and glaucomatous eyes were of less significance. The P1 peak time difference between black-white and black-red checkerboards may serve as an important parameter in the early diagnosis of glaucoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Abbreviations

OH:

ocular hypertension

POAG:

primary open-angle glaucoma

NC:

normal control

CPRVEP:

color pattern-reversal visual evoked potential

References

  1. Towle UL, Moskowitz AN, Sokol S, Schwartz BN. The VHP in glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci 1983: 24: 175–83.

    Google Scholar 

  2. Rouland JF, Hache JC. Visual-evoked potentials in glaucoma and ocular hypertension. Glaucoma 1990; 12: 77–78.

    Google Scholar 

  3. Bellizzi M, Cardia L, Lamorgese C, Pomes L, Sorrento G, Ferrante G. Pattern visual-evoked potentials in early diagnosis of open-angle glaucoma. Glaucoma 1988; 10: 60–61.

    Google Scholar 

  4. Bobak P, Bodis-wollner I, Harnois C, Maffei L, Mylin L, Podos S, Thornton J. Pattern ERGs and VEPs in glaucoma and multiple sclerosis. Am J Ophthalmol 1983; 96: 72–83.

    Google Scholar 

  5. Izumi Nakajima, Emiko Adachi. Pattern VECPs in ocular hypertension. Folia Ophthalmol Jpn 1984; 35: 1556–60.

    Google Scholar 

  6. Jian GE, Lezheng WU, Dezheng WU. Color pattern visual evoked potential in glaucomatous optic nerve atrophy. Eye Science 1986; 2: 154–57.

    Google Scholar 

  7. Huang T-t. The correspondence of Zi-ping Yu, Ishihara plates for color vision. Chinese J Ophthalmol 1965; 12: 84–86.

    Google Scholar 

  8. Coganek L, Ingvar DH. Color specific features of visual cortical responses in man evoked by monochromatic flashes. Acta Physiol Scand 1969; 76: 82–92.

    Google Scholar 

  9. Wu W-C, Liu J-y, Zheng Z-l. Analysis of color evoked potentials in man. Acta Biochimica et Biophysica Sinica 1985; 6: 26–29.

    Google Scholar 

  10. Vingrys AJ, King-smith PE, Benes SC. Equiluminous color deficits are greater than achromatic losses in cases of toxoplasmosis. In: Drum B, Verriest G, eds. Dordrecht/Boston/London: Kluwer Academic Publishers, 1987: 217–27.

    Google Scholar 

  11. Quigley HA, Addioks EM, Green WR, Maumenee AE. Optic nerve damage in human glaucoma. Arch Ophthalmol 1981; 99: 635–49.

    Google Scholar 

  12. Atkin A, Wollner IB, Wolkstein M, Moss A, Podos SM. Abnormalities of central contrast sensitivity in glaucoma. Am J Ophthalmol 1979; 88: 205–11.

    Google Scholar 

  13. Ross JE, Bron AJ, Reeves BC, Emmerson PG. Detection of optic nerve damage in ocular hypertension. Br J Ophthalmol 1985; 69: 897–903.

    Google Scholar 

  14. Adams AJ, Rodic R, Husted R, Stamper R. Spectral sensitivity color discrimination changes in glaucoma and glaucoma-suspect patients. Invest Ophthalmol Vis Sci 1982; 23: 516–24.

    Google Scholar 

  15. Drance SM, Lanowski R, Schulzer M, Douglas GR. Acquired color vision changes in glaucoma. Arch Ophthalmol 1981; 99: 829–36.

    Google Scholar 

  16. Stamper RL. The effect of glaucoma on central visual function. Trans Am Ophthalmol Soc 1984; 82: 792–826.

    Google Scholar 

  17. Huang Z-j, Chang C-e. Dark adaptation in primary glaucoma. Transaction of the 1964 annual conference of Beijing association in ophthalmology, 1964: 34–36.

  18. Trich GL. Retinal potentials in patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci 1985; 26: 1750–58.

    Google Scholar 

  19. Ikeda H, Tremain KE, Sanders MD. Neurophysiological investigation in optic nerve disease: combined assessment of VEP and ERG. Br J Ophthalmol 1978; 62: 227–39.

    Google Scholar 

  20. Fishman RS. The visual-evoked cortical response in nightblindness. Am J Ophthalmol 1966; 62: 1166–76.

    Google Scholar 

  21. Sokol S. VEPs: theory, techniques and clinical applications. Survey Ophthalmol 1976; 21: 18–44.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Beijing Institute of Ophthalmology, Beijing, China

    Yi-Hao Shih MD, Zhu-Jing Huang & Ching-E Chang

Authors
  1. Yi-Hao Shih MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zhu-Jing Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ching-E Chang
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shih, YH., Huang, ZJ. & Chang, CE. Color pattern-reversal visual evoked potential in eyes with ocular hypertension and primary open-angle glaucoma. Doc Ophthalmol 77, 193–200 (1991). https://doi.org/10.1007/BF00161367

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00161367

Key words

Search

Navigation