May 2014, Volume 25, Issue 5, pp 1439-1443,
Open Access This content is freely available online to anyone, anywhere at any time.
Date: 28 Feb 2014
The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group
Osteoporosis causes an elevated fracture risk. We propose the continued use of T-scores as one means for diagnosis but recommend that, alternatively, hip fracture; osteopenia-associated vertebral, proximal humerus, pelvis, or some wrist fractures; or FRAX scores with ≥3 % (hip) or 20 % (major) 10-year fracture risk also confer an osteoporosis diagnosis.
Osteoporosis is a common disorder of reduced bone strength that predisposes to an increased risk for fractures in older individuals. In the USA, the standard criterion for the diagnosis of osteoporosis in postmenopausal women and older men is a T-score of ≤ −2.5 at the lumbar spine, femur neck, or total hip by bone mineral density testing.
Under the direction of the National Bone Health Alliance, 17 clinicians and clinical scientists were appointed to a working group charged to determine the appropriate expansion of the criteria by which osteoporosis can be diagnosed.
The group recommends that postmenopausal women and men aged 50 years should be diagnosed with osteoporosis if they have a demonstrable elevated risk for future fractures. This includes having a T-score of less than or equal to −2.5 at the spine or hip as one method for diagnosis but also permits a diagnosis for individuals in this population who have experienced a hip fracture with or without bone mineral density (BMD) testing and for those who have osteopenia by BMD who sustain a vertebral, proximal humeral, pelvic, or, in some cases, distal forearm fracture. Finally, the term osteoporosis should be used to diagnose individuals with an elevated fracture risk based on the World Health Organization Fracture Risk Algorithm, FRAX.
As new ICD-10 codes become available, it is our hope that this new understanding of what osteoporosis represents will allow for an appropriate diagnosis when older individuals are recognized as being at an elevated risk for fracture.
NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy (2001) NIH consensus development panel on osteoporosis prevention, diagnosis and treatment. Osteoporosis prevention, diagnosis, and therapy. JAMA 285(6):785–795CrossRef
National Osteoporosis Foundation. Clinician’s guide to prevention and treatment of osteoporosis. http://nof.org/hcp/resources/913. Accessed 18 Oct 2013
US Department of Health and Human Services. Bone health and osteoporosis: a report of the surgeon general. http://www.surgeongeneral.gov/library/reports/bonehealth/. Accessed 18 Oct 2013
Watts NB, Bilezikian JP, Camacho PM et al (2010) American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract 16(Suppl 3):1–37PubMed
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- The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group
- Open Access
- Available under Open Access This content is freely available online to anyone, anywhere at any time.
Volume 25, Issue 5 , pp 1439-1443
- Cover Date
- Print ISSN
- Online ISSN
- Springer London
- Additional Links
- Clinical diagnosis
- Position statement
- Industry Sectors
- Author Affiliations
- 1. Division of Endocrinology, Department of Medicine, Columbia University Medical Center, New York, NY, USA
- 2. School of Medicine, Virginia Commonwealth University, Richmond, VA, USA
- 3. Bethesda Health Research, Bethesda, MD, USA
- 4. Jean Mayer USDA Human Nutrition Research Center on Aging, Bone Metabolism Laboratory, Tufts University, Boston, MA, USA
- 5. Department of Medicine, University of Chicago, Chicago, IL, USA
- 6. Department of Endocrinology and Metabolism, University of California, San Francisco, CA, USA
- 7. Division of Endocrinology, Johns Hopkins University, Baltimore, MD, USA
- 8. Mayo Clinic, Rochester, MN, USA
- 9. School of Medicine, University of California, Davis, CA, USA
- 10. Helen Hayes Hospital, West Haverstraw, NY, USA
- 11. University of North Texas Health Science Center, Fort Worth, TX, USA
- 12. Oregon Health & Science University, Portland, OR, USA
- 13. Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, AL, USA
- 14. Bone Health Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA
- 15. Osteoporosis and Bone Health Services, Mercy Health Physicians, Cincinnati, OH, USA