A Practical Approach to Interpretation of Dual-Energy X-ray Absorptiometry (DXA) for Assessment of Bone Density
Osteoporosis is an extremely common disorder that may result in fractures in several locations. Hip fractures associated with osteoporosis can result in mortality. The defining characteristic of osteoporosis is reduced bone mineral density as identified by dual energy X-ray absorptiometry (DXA). Depending on specific factors, related to the clinical status of the patient or technical aspects of the test itself, interpretation of a DXA examination ranges from straightforward to complicated. We present an approach to evaluation of these factors and production of a clinically relevant report. In this approach, initial screening examinations are regarded as straightforward, follow-up examinations are mildly complex, and examinations that require recalculation of data are complex.
- U.S. Department of Health and Human Services. Bone health and osteoporosis: A report of the surgeon general. Rockville, MD: U.S. Department of Health and Human Services, Office of the Surgeon General, 2004. http://www.surgeongeneral.gov/library. Accessed February 2014.
- Center JR, Bliuc D, Nguyen TV, Eisman JA. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007;297:387–94. CrossRef
- Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res. 2007;22:465–75. CrossRef
- Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9:1137–41. CrossRef
- Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008;19:385–97. CrossRef
- Wood K, Dhital S, Chen H, Sippel R. What is the utility of distal forearm DXA in primary hyperparathyroidism? Oncologist. 2012;17:322–5. CrossRef
- Peel NF, Johnson A, Barrington NA, Smith TW, Eastell R. Impact of anomalous vertebral segmentation on measurements of bone mineral density. J Bone Miner Res. 1993;8:719–23. CrossRef
- Bonnick SL. A statistical overview for the non-statistician densitometrist. Bone densitometry in clinical practice: application and interpretation. New York: Humana; 2010. p. 79–104. CrossRef
- ISCD Official Positions. http://www.iscd.org/official-positions/2013-iscd-official-positions-adult/. Accessed February 2014.
- Bonnick SL. Monitoring change in bone density. Bone densitometry in clinical practice: application and interpretation. New York: Humana; 2010. p. 257–78. CrossRef
- ISCD Resources Calculators. http://www.iscd.org/resources/calculators/ Accessed February 2014.
- A Practical Approach to Interpretation of Dual-Energy X-ray Absorptiometry (DXA) for Assessment of Bone Density
Current Radiology Reports
- Online Date
- April 2014
- Online ISSN
- Springer US
- Additional Links
- Dual energy X-ray absorptiometry (DXA)
- Bone mineral density
- Author Affiliations
- 1. Department of Radiology, Indiana University School of Medicine, UH0279, 500N. University Blvd, Indianapolis, IN, 46202-5253, USA
- 2. Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157-1088, USA