Rapid Diagnosis of Primary Dengue Fever by the Immunochromatographic Test and by Electron Microscopy – A Case Report
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- Allwinn, R., Schieferstein, C., Glauke, S. et al. Infection (1999) 27: 365. doi:10.1007/s150100050045
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A 21-year-old women presented with an acute febrile illness after a two-week holiday in Jamaica. Her symptoms started two days after return, with sudden onset of continuous higher fever (> 39 °C), dizziness and nausea. Three days later she developed a generalized macular rash, which led to the tentative diagnosis “acute dengue fever”. Laboratory confirmation was achieved by demonstrating anti-dengue IgM and IgG antibodies in paired sera; in addition, flavivirus particles were directly visualized by electron microscopy.