Acute Disseminated Encephalomyelitis (ADEM) Due to Mycoplasma pneumoniae Infection in an Adolescent
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- Riedel, K., Kempf, V., Bechtold, A. et al. Infection (2001) 29: 240. doi:10.1007/s15010-001-1173-z
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A 17-year-old boy presented with a severe form of an acute disseminated encephalomyelitis (ADEM) with hemiparesis and coma after initial symptoms of a flu-like febrile infection 1 week previously. Titers against Mycoplasma pneumoniae were significantly increased in serum and cerebrospinal fluid (CSF). Detection of M. pneumoniae was achieved in the initial CSF sample using M. pneumoniae-specific PCR. The patient improved significantly on antimicrobial therapy with erythromycin and immunosupressive therapy with immunoglobulins and corticosteroids. This case report demonstrates a well-documented course of a central nervous system (CNS) infection resulting in the ADEM syndrome.