, Volume 25, Issue 9, pp 1515-1520
Date: 13 Jun 2014

Direct Analysis of Large Living Organism by Megavolt Electrostatic Ionization Mass Spectrometry

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A new ambient ionization method allowing the direct chemical analysis of living human body by mass spectrometry (MS) was developed. This MS method, namely Megavolt Electrostatic Ionization Mass Spectrometry, is based on electrostatic charging of a living individual to megavolt (MV) potential, illicit drugs, and explosives on skin/glove, flammable solvent on cloth/tissue paper, and volatile food substances in breath were readily ionized and detected by a mass spectrometer.