Tolerance of baby cleansers in infants: A randomized controlled trial
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This randomized controlled trial was conducted to evaluate the tolerability of a new baby cleanser formulation — Johnson’s Top-to-Toe cleanser (JTT) on infantile skin. 180 healthy infants (60 in each group) were enrolled and JTT Sebamed Baby Liquid cleanser (SM), and lukewarm tap water were used on the skin of the subjects as whole body cleansers twice a week for 2 weeks. Assessment was done at baseline, 1 week and 2 weeks clinically by a dermato-logist, instrumentally, and by the parents. Clinical assessment (erythema, edema, dryness and scaling); skin moisture content; skin surface pH; trans-epidermal water loss; skin oxyhemoglobin and deoxyhemoglobin; and consu-mer satisfaction were the outcome measures. There was no significant erythema, edema, dryness, or scaling elicited by any of the three test components. Parents did not report any side-effects. All the three studied interventions used as whole body cleansers were efficacious and well tolerated by infants.
- Sarkar R. Care of the skin. In: Gupta P (editor). Essential Pediatric Nursing. New Delhi: CBS Publisher and Distributors; 2007. p. 217–226.
- Schmid Wendtner MH, Korting Hl. The pH of the skin surface and its impact on the barriers function. Skin Pharmacol Physiol 2006; 19: 296–302. CrossRef
- Gfatter R, Hackl P, Braun F. Effects of soap and detergents on skin surface pH, stratum corneum hydration and fat content in infants. Dematology 1997; 195: 258–262. CrossRef
- Tyebkan G. Skin cleansing in neonates and infantsbasics of cleansers. Indian J Pediatr 2002; 69: 767–769. CrossRef
- Dhar S. Newborn skin care revisited. Indian J Dematol 2007 52: 1–4. CrossRef
- Giusti F, Martella A, Bertoni L, Seidenarr S. Skin barrier, hydration and pH of the skin of infants under 2 year of age. Pediatr Dematol 2001; 18: 93–96. CrossRef
- Wilhelm KP, Civa A, Maibach H. Skin aging: Effect on transepidermal water loss, stratum corneum hydration, skin surface pH and casual sebum content. Arch Dematol 1991; 127: 1806–1809. CrossRef
- Thibodeau A, Amari. S. Maintenance and repair of the hydrolipidic film with skin molecular mimetic emollients and surfactants. Available from: www.cosmeticsciencetechnology.com/companies/articles/1751.pdf. Accessed on 28th June, 2009.
- Draelos ZD. Sensitive skin: perceptions, evaluation and treatment. Am J Contact Dermat 1997; 8: 67–68. CrossRef
- Ananthapadmanabhan KP, Moore DJ, Subramanyam K, Misra M, Meyer F. Cleansing without compromise:the imact of cleansers on the skin barrier and the technology of mild cleansing. Dermatol Ther 2004;17(Supl): 16–25. CrossRef
- Kuehl BL, Fyfe KS, Shear NH. Cutaneous cleansers. Skin therapy 2003; 8: 1–4.
- Morelli JG, William WL. Soaps and shampoos in pediatric practice. Pediatrics 1987; 5: 634–637.
- Peck SM, Kantor I, Bioday M. Alkaline toilet.soaps are not the cleanser of choice in routine pediatric care. A cross-over study comparing alkaline toilet soap against a neutral detergent as a routine cleansers. Clin Pediatr 1964; 3: 42–45. CrossRef
- Tyebkhan G. A study in the pH of the various soaps available in the Indian market. Indian J Dermatol Venereol Leprol 2001; 67: 290–291.
- Tolerance of baby cleansers in infants: A randomized controlled trial
Volume 47, Issue 11 , pp 959-963
- Cover Date
- Print ISSN
- Additional Links
- Baby cleanser
- Epidermal water loss
- Author Affiliations
- 1. University of Santo Tomas Hospital, Manila, Philippines
- 5. Department of Dermatology, University of Santo Tomas, Espana, Manila, Philippines
- 2. Asia-Pacific Skin Testing Centre, Metro Manila, Philippines
- 3. Johnson & Johnson Pacific Pvt Ltd, NSW, Australia
- 4. Safdarjung Hospital, New Delhi, India