Macromolecular Research

, Volume 21, Issue 8, pp 892–898

Preparation and characterization of calcium phosphate cement of α-tricalcium phosphate-tetracalcium phosphate-dicalcium phosphate system incorporated with poly(γ-glutamic acid)

  • Young Baek Kim
  • Byung Min Lee
  • Myung Chul Lee
  • Insup Noh
  • Sung-Jae Lee
  • Sung Soo Kim
Article

DOI: 10.1007/s13233-013-1109-3

Cite this article as:
Kim, Y.B., Lee, B.M., Lee, M.C. et al. Macromol. Res. (2013) 21: 892. doi:10.1007/s13233-013-1109-3

Abstract

Polymeric calcium phosphate cements (PCPCs) were prepared from cement powders consisting of alphatricalcium phosphate (α-TCP), tetracalcium phosphate (TTCP) and dicalcium phosphate (DCP), and cement liquid with poly(γ-glutamic acid) (γ-PGA). The characteristics of calcium phosphate cements (CPCs), such as paste injectability, initial setting time, and compressive strength, were assessed. The injectability of PCPCs with a 0–30 wt% TTCP/DCP mixture was above 90%. The initial setting time decreased in concert with the amount of incorporated TTCP/DCP mixture and reached approximately 10–13 min when the amount of TTCP/DCP mixture was 10–30 wt%. The compressive strength of PCPC with the 30% equimolar TTCP/DCP mixture was approximately 18.4±3.5 MPa, whereas that of the CPC without the TTCP/DCP mixture was approximately 4.8±0.1 MPa.

Keywords

calcium phosphate cement poly(γ-glutamic acid) tricalcium phosphate tetracalcium phosphate 

Copyright information

© The Polymer Society of Korea and Springer Sciene+Business Media Dordrecht 2013

Authors and Affiliations

  • Young Baek Kim
    • 1
  • Byung Min Lee
    • 2
  • Myung Chul Lee
    • 3
  • Insup Noh
    • 4
  • Sung-Jae Lee
    • 5
  • Sung Soo Kim
    • 2
  1. 1.Department of NanotechnologyPaiChai UniversityDaejeonKorea
  2. 2.Korea Research Institute of Chemical TechnologyDaejonKorea
  3. 3.Department of Orthopedic SurgerySeoul National University HospitalSeoulKorea
  4. 4.Department of Chemical and Biomacromolecular EngineeringSeoul National University of Science and TechnologySeoulKorea
  5. 5.Department of Biomedical EngineeringInje UniversityGyeongnamKorea