Macromolecular Research

, Volume 18, Issue 1, pp 59–66

Synthesis of poly(vinyl alcohol) (PVA) nanofibers incorporating hydroxyapatite nanoparticles as future implant materials

  • Faheem A. Sheikh
  • Naseer A. M. Barakat
  • Muzafar A. Kanjwal
  • Soo Jin Park
  • Dae Kwang Park
  • Hak Yong Kim
Articles

DOI: 10.1007/s13233-009-0111-2

Cite this article as:
Sheikh, F.A., Barakat, N.A.M., Kanjwal, M.A. et al. Macromol. Res. (2010) 18: 59. doi:10.1007/s13233-009-0111-2

Abstract

This study examined the mechanical properties of a disc consisting of electrospun poly(vinyl alcohol) (PVA) nanofibers incorporated with high purity hydroxyapatite (HAp) nanoparticles (NPs) for potential hard tissue engineering applications. As HAp NPs are insoluble in a PVA aqueous solution, electrospinning of a colloidal solution was used instead of the conventional process, which is based on completely miscible solutions. The PVA/HAp colloidal solutions were characterized by dynamic light scattering (DLS) and electrophoratic light scattering (ELS), which indicated a unimodal size distribution and negative zeta potential. The physiochemical characterizations confirmed the production of PVA electrospun nanofibers incorporating HAp NPs. To investigate the bioactivity of the produced nanofiber mats, compacted mats with a disc shape were incubated in stimulated body fluid (SBF) at 37 °C for 6 days. SEM indicated that the incorporation of HAp strongly activates the precipitation of the apatite-like materials because the HAp NPs act as seeds that accelerate the crystallization of biological HAp from the utilized SBF.

Keywords

electrospinning nanofibers nanoparticles hydroxyapatite implant 

Copyright information

© The Polymer Society of Korea and Springer Netherlands 2010

Authors and Affiliations

  • Faheem A. Sheikh
    • 1
  • Naseer A. M. Barakat
    • 2
  • Muzafar A. Kanjwal
    • 3
  • Soo Jin Park
    • 4
  • Dae Kwang Park
    • 5
  • Hak Yong Kim
    • 5
  1. 1.Department of Bionano System EngineeringChonbuk National UniversityJeonjuKorea
  2. 2.Chemical Engineering Department, Faculty of EngineeringEl-Minia UniversityEl-MiniaEgypt
  3. 3.Department of Polymer Nano Science and TechnologyChonbuk National UniversityJeonjuKorea
  4. 4.Center for Healthcare Technology DevelopmentChonbuk National UniversityJeonjuKorea
  5. 5.Department of Textile EngineeringChonbuk National UniversityJeonjuKorea

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