Journal of Cancer Education

, Volume 28, Issue 2, pp 319–324

Prevalence, Risk Factors, and Disease Knowledge of Chronic Hepatitis B Infection in Vietnamese Americans in California


  • Nghi B. Ha
    • Pacific Health Foundation
    • School of PharmacyUniversity of California San Francisco
  • Huy N. Trinh
    • Song Manh, Inc
  • Trang T. Nguyen
    • Song Manh, Inc
  • Truong-Sinh Leduc
    • Leduc Medical Group
  • Christopher Bui
    • Christopher Duong Bui MD Inc
  • Nghiem B. Ha
    • Division of Gastroenterology and Hepatology, Department of MedicineStanford University Medical Center
    • Pacific Health Foundation
  • Carrie R. Wong
    • Stony Brook University School of Medicine
    • Pacific Health Foundation
  • Anh Thu Tran
    • Song Manh, Inc
    • Division of Gastroenterology and Hepatology, Department of MedicineStanford University Medical Center
    • Division of Gastroenterology and HepatologyStanford University Medical Center

DOI: 10.1007/s13187-013-0466-0

Cite this article as:
Ha, N.B., Trinh, H.N., Nguyen, T.T. et al. J Canc Educ (2013) 28: 319. doi:10.1007/s13187-013-0466-0


Our goal is to examine the prevalence, risk factors, and disease knowledge of chronic hepatitis B (CHB) among Vietnamese Americans in California. We also examined treatment eligibility and linkage to care among patients who tested positive for CHB. We enrolled 717 subjects from ten different hepatitis B virus (HBV) screening events in five locations from January 2009 to June 2010 in California. HBV status was determined by hepatitis B surface antigen (HBsAg) and antibody. Data were collected by a 36-question survey. A total of 99 patients (13.8 %) had positive HBsAg, especially those aged 31–40 years (23.6 %), and 177 (24.7 %) were still susceptible to HBV infection. A significant proportion of those who were HBsAg positive or still susceptible reported a history of HBV vaccination (10 and 20 %, respectively). Following adjustments for age and sex, significant predictors for HBsAg positivity were lack of healthcare coverage (OR = 2.4, p = 0.004), having a family history of CHB (OR = 2.1, p = 0.009), and prior occupational exposure (OR = 3.0, p = 0.007). Of those who tested positive, 13.3 % met criteria for antiviral therapy, but none had been initiated on treatment. HBV prevalence in Vietnamese Americans in California was high (13.8 %), especially in those between 31 and 40 years of age. Patient disease and treatment knowledge was poor, as were follow-up and management of those found to have CHB and/or have indication for antiviral therapy.



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© Springer Science+Business Media New York 2013