, Volume 47, Issue 2, pp 143-145
Date: 23 Nov 2012

A Papillary Thyroid Tumor Detected by 18F-FDG-PET/CT in a Pediatric Patient with Cowden Syndrome

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We describe a papillary thyroid tumor detected by fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in a 11-year-old male patient with Cowden syndrome. 18F-FDG-PET/CT was performed for restaging of a germ cell tumor previously treated. A focal area of increased 18F-FDG uptake in the right thyroid lobe was detected. Based on this PET/CT finding, the patient underwent an ultrasonography guided fine needle aspiration biopsy which showed the presence of a papillary thyroid carcinoma. In this rare case of Cowden syndrome 18F-FDG-PET/CT has been useful in the early detection of a pediatric thyroid cancer (Figs. 1 and 2).Fig. 1

We report the case of a 11-year-old male patient affected by Cowden syndrome (CS) which is a rare inherited disorder characterized by multiple hamartomas and an increased risk of certain forms of cancer [1]. The patient underwent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT ...