, Volume 4, Issue 3, pp 216-223
Date: 28 Jun 2012

Role of Mammography versus Magnetic Resonance Imaging for Breast Cancer Screening

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Abstract

Mammographic screening has been proven to detect breast cancer at an early stage and to reduce mortality from breast cancer. Nevertheless, some limitations concerning sensitivity, as well as adverse effects such as false negatives and radiosensitivity, has led to a need to search for other screening techniques. Magnetic resonance imaging has been an excellent choice for some specific subgroups, including patients at high risk. However, high cost, low availability, and lack of long-term trials aiming to prove the reduction of mortality have limited magnetic resonance application. Moreover, some points about breast cancer screening still need to be clarified, including overdiagnosis rate, which includes cancers that would not have become clinically significant during the woman’s lifetime, and cost effectiveness. In this review, the authors analyze the role of mammography and magnetic resonance imaging in breast cancer screening for the general and high-risk populations.