The journal of nutrition, health & aging

, Volume 15, Issue 8, pp 618–622

Better cognitive and physical performance is associated with higher blood pressure in centenarians

  • Jan Szewieczek
  • J. Dulawa
  • J. Gminski
  • A. Kurek
  • K. Legierska
  • T. Francuz
  • I. Włodarczyk-Sporek
  • M. Janusz-Jenczen
  • B. Hornik
Better Cognitive, Physical Performance is Associated with Higher Blood Pressure

DOI: 10.1007/s12603-011-0334-8

Cite this article as:
Szewieczek, J., Dulawa, J., Gminski, J. et al. J Nutr Health Aging (2011) 15: 618. doi:10.1007/s12603-011-0334-8
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Abstract

Objectives

Knowledge of rational, evidence based health care in the hundred-year-old is still poor. The aim of the study was to evaluate health and functional state in hundred-year-old inhabitants of Upper Silesia, Poland, with a focus on the heart and vascular function.

Participants

Medical and nursing assessment at places of residence was performed in thirty five 100.7±1.4 (meant SD) year-old subjects, 28 women, and 7 men.

Measurements

The protocol included Mini-Mental State Examination (MMSE), Barthel Index (BI) and laboratory tests. A telephone follow-up was performed 180 days after the initial examination.

Results

Most subjects had increased systolic blood pressure (BP), diminished albumin and folate serum levels as well as decreased Glomerular Filtration Rate. According to the quadratic polynomial regression model MMSE and BI were dependent on BP. Higher BP was associated with better performance and survival. Those who survived more than 180 days had lower levels of CRP and VCAM-1 and higher level of sCD40L.

Conclusion

The relationships between functional scales, survival and blood pressure suggest a beneficial effect of elevated BP on both mental and physical performance in centenarians. Further studies should determine an optimal balance between risk and benefits of elevated blood pressure in the oldest old people.

Key words

Centenarianscognitive functionactivities of daily livingblood pressuresICAM-1sVCAM-1sP-selectinsCD40LVEGF

Copyright information

© Serdi and Springer Verlag France 2011

Authors and Affiliations

  • Jan Szewieczek
    • 1
    • 4
  • J. Dulawa
    • 2
  • J. Gminski
    • 3
  • A. Kurek
    • 4
  • K. Legierska
    • 2
  • T. Francuz
    • 3
  • I. Włodarczyk-Sporek
    • 1
  • M. Janusz-Jenczen
    • 1
  • B. Hornik
    • 1
  1. 1.Department of Internal NursingMedical University of SilesiaKatowicePoland
  2. 2.Department of Internal Medicine and Metabolic DiseasesMedical University of SilesiaKatowicePoland
  3. 3.Department of BiochemistryMedical University of SilesiaKatowicePoland
  4. 4.Department of GeriatricsMedical University of SilesiaKatowicePoland
  5. 5.Department of GeriatricsSPSK NR 7 SUM GCMKatowicePoland