The journal of nutrition, health & aging

, Volume 15, Issue 1, pp 65–70

A practical approach to lipid management in the elderly

Article

DOI: 10.1007/s12603-011-0014-8

Cite this article as:
Viljoen, A. J Nutr Health Aging (2011) 15: 65. doi:10.1007/s12603-011-0014-8

Abstract

Cardiovascular disease (CVD) increases in a curvilinear fashion after 65 years in men and 75 years in women and the majority of all cardiovascular events occur in individuals older then 65 years. There are notable differences in the clinical assessment of hyperlipidaemia, cardiovascular risk estimation as well as the safety and tolerability profiles in the elderly compared to younger individuals. Clinical trial data have now demonstrated the benefits of statin treatment in the elderly in both the primary and secondary prevention settings. There is however limited data for individuals older than 80 years. Little data is available on other lipid modifying medication in the elderly. With continuing increases in average life expectancy, preventive efforts will become increasingly important for preventing morbidity, improving quality of life, and reducing healthcare expenditures for older persons. This emphasizes the importance of clinical decisionmaking and weighing up the risks and benefits of treatment.

Key words

Lipid managementelderlycardiovascular disease

Non-standard abbreviations

CVD

cardiovascular disease

LDL-C

low density lipoprotein cholesterol

HDL

high density lipoprotein

TG

triglycerides

TC

total cholesterol

CYP

cytochrome P450

ALT

alanine amino transferase

AST

aspartate amino transferase

Copyright information

© Serdi and Springer Verlag France 2011

Authors and Affiliations

  1. 1.Department of Chemical PathologyLister HospitalStevenageUK
  2. 2.Bedfordshire and Hertfordshire Postgraduate Medical SchoolPutteridge Bury CampusLutonUK