JNHA - The Journal of Nutrition, Health and Aging

, 13:760

The effect of a nutrient dense drink on mental and physical function in institutionalized elderly people

Authors

  • M. Manders
    • Division of Human NutritionWageningen University
    • Division of Human NutritionWageningen University
  • W. H. L. Hoefnagels
    • Department of GeriatricsRadboud University Nijmegen Medical Centre
    • Division of Human NutritionWageningen University
    • Division of Human NutritionWageningen University
  • W. Wouters-Wesseling
    • DMV International
  • A. J. M. J. Mulders
    • Nursing Home De Landrijt
  • W. A. Van Staveren
    • Division of Human NutritionWageningen University
Enriched Drink, Mental and Physical Function

DOI: 10.1007/s12603-009-0211-x

Cite this article as:
Manders, M., De Groot, L.C.P.G.M., Hoefnagels, W.H.L. et al. J Nutr Health Aging (2009) 13: 760. doi:10.1007/s12603-009-0211-x

Abstract

Objectives

To determine whether in the current study the supply of a nutrient dense drink has a positive effect on mental and physical function of institutionalized elderly people.

Design

A 24-week, randomized, double-blind, placebo-controlled, parallel-group, intervention trial.

Setting

Homes for the elderly and nursing homes in the Netherlands.

Participants

Institutionalized elderly people older than 60 years, with a BMI ≤ 30 kg/m2, and a Mini-Mental State Examination score of at least 10 points.

Intervention

In addition to their usual diet the participants (n=176) received either a nutrient dense drink or a placebo drink twice a day during 24 weeks.

Measurements

The functionality measures included cognitive function, mood, physical performance and the ability to perform activities of daily living.

Results

In the supplement group a favorable effect of the intervention drink on body weight (1.6 kg difference in change; P =.035), calf circumference (0.9 cm difference in change; P =.048), and blood values (e.g. Hcy decreased from 16.8 to 11.2 µmol/L in the supplement group) was found. In the total group no significant effect was found on functionality outcomes. However, a subgroup of participants with BMI at baseline below 24.4 kg/m2 performed better on the cognitive subscale of Alzheimer’s Disease Assessment Scale (P =.09), and its language sub score (P =.01) after 24 weeks of intervention.

Conclusion

The results in the total group of this trial suggest that the nutritional supplement used in this study improves nutritional status. Furthermore, the results of this trial suggest that it is effective as treatment for decreasing function in a subgroup of institutionalized elderly people with low BMI.

Key words

Institutionalized elderly peoplefunctionmicronutrientsrandomized clinical trial

Copyright information

© Serdi and Springer Verlag France 2009