Health and Technology

, Volume 3, Issue 4, pp 271–281

Diagnostic tools and technologies for infectious and non-communicable diseases in low-and-middle-income countries

Original Paper

DOI: 10.1007/s12553-013-0060-9

Cite this article as:
Novak, M.T., Kotanen, C.N., Carrara, S. et al. Health Technol. (2013) 3: 271. doi:10.1007/s12553-013-0060-9

Abstract

The challenge of changing the healthcare outcomes of many in low- and middle-income countries (LMICs) looms as a major potential cost to all of humankind. A majority of global health initiatives have focused upon increasing access and innovation in treatment options. However, the reliable and appropriate use of candidate treatments must be preceded by diagnoses that ensure the correct clinical path. Foremost in addressing this challenge is the need to develop and distribute appropriate, low cost, accessible diagnostic technologies to engender quality care. Such a need is pressing, for both communicable and non-communicable diseases, which continue to present a growing burden to LMICs. The emergence of paper diagnostics, microfluidic-based total analytical systems (μTAS), BioMEMS, and nano-inspired bioanalytical biosensors; which by their very sophistication promise to render diagnostic tests simple and potentially widely affordable, present exciting options to addressing this need. This paper discusses complementary policy issues in regulation and procurement that must be considered to make low cost, point of care diagnostic technology an accepted step in patient care within LMICs and presents a number of emerging technologies that are poised to address this need.

Keywords

Low-cost diagnostics ASSURED Paper diagnostics Micro-TAS Lateral-flow-devices 

Copyright information

© IUPESM and Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of Biomedical EngineeringDuke UniversityDurhamUSA
  2. 2.Center for Bioelectronics, Biosensors and Biochips (C3B)Clemson University Advanced Materials CenterAndersonUSA
  3. 3.EPFL – École Polytechnique Fédérale de LausanneLausanneSwitzerland
  4. 4.Department of Chemical and Biomolecular EngineeringClemson UniversityClemsonUSA
  5. 5.World Health OrganizationGenevaSwitzerland

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