Biophysical Reviews

, Volume 3, Issue 4, pp 171–184

Luminescent nanodiamonds for biomedical applications

Authors

  • Jana M. Say
    • ARC Centre of Excellence for Engineered Quantum Systems, Department of Physics and AstronomyMacquarie University
    • Department of Chemistry and Biomolecular SciencesMacquarie University
  • Caryn van Vreden
    • School of Medical Sciences, Bosch Institute, Department of PathologyThe University of Sydney
  • David J. Reilly
    • ARC Centre of Excellence for Engineered Quantum Systems, The School of PhysicsThe University of Sydney
  • Louise J. Brown
    • Department of Chemistry and Biomolecular SciencesMacquarie University
    • ARC Centre of Excellence for Engineered Quantum Systems, Department of Physics and AstronomyMacquarie University
    • School of Medical Sciences, Bosch Institute, Department of PathologyThe University of Sydney
Review

DOI: 10.1007/s12551-011-0056-5

Cite this article as:
Say, J.M., van Vreden, C., Reilly, D.J. et al. Biophys Rev (2011) 3: 171. doi:10.1007/s12551-011-0056-5

Abstract

In recent years, nanodiamonds have emerged from primarily an industrial and mechanical applications base, to potentially underpinning sophisticated new technologies in biomedical and quantum science. Nanodiamonds are relatively inexpensive, biocompatible, easy to surface functionalise and optically stable. This combination of physical properties are ideally suited to biological applications, including intracellular labelling and tracking, extracellular drug delivery and adsorptive detection of bioactive molecules. Here we describe some of the methods and challenges for processing nanodiamond materials, detection schemes and some of the leading applications currently under investigation.

Keywords

NanodiamondNitrogen-vacancy centreFluorescenceImagingBiofunctionalisationDrug delivery

Copyright information

© International Union for Pure and Applied Biophysics (IUPAB) and Springer 2011