International Journal of Precision Engineering and Manufacturing

, Volume 12, Issue 1, pp 169–173

Comparison of gait and cognitive function among the elderly with Alzheimer’s Disease, Mild Cognitive Impairment and Healthy

Authors

  • Jin-Seung Choi
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Ho-Sang Oh
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Dong-Won Kang
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Kyung-Ryul Mun
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Mi-Hyun Choi
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Su-Jeong Lee
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Jae-Woong Yang
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Soon-Cheol Chung
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
  • Suk-Woo Mun
    • Department of Psychiatry, School of MedicineKonkuk University
    • Department of Biomedical EngineeringKonkuk University & Research Institute of Biomedical Engineering
Article

DOI: 10.1007/s12541-011-0024-9

Cite this article as:
Choi, J., Oh, H., Kang, D. et al. Int. J. Precis. Eng. Manuf. (2011) 12: 169. doi:10.1007/s12541-011-0024-9

Abstract

The purpose of this study was to compare gait pattern and cognitive function among elderly patients with Alzheimer’s Disease (AD), elderly people with Mild Cognitive Impairment (MCI), and Healthy Controls (HC). Twenty three elderly patients participated: 10 AD (77.2±6.84 yrs), 7 MC I(72.9±6.28 yrs), and 6 HC (71.6±5.78 yrs). Gait and Cognitive function were collected using an accelerometer attached to the foot and the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease (CREAD-K), respectively. To compare differences in gait performance among groups, mean stride time, magnitude and structure of gait variability and ratio of low frequency and high frequency (LF/HF ratio) of stride time sequence were used in this study. Results showed that gait variables (mean stride time, LF/HF ratio of stride time) were useful for classification between MCI and HC. Cognitive function (T1, T3, T4, T6, and T8 of CREAD-K) represented the difference between AD and HC. This study may provide a foundation for future work on progression of dementia.

Keywords

Alzheimer’s Disease Mild Cognitive Impairment Gait Cognitive test Elderly

Copyright information

© Korean Society for Precision Engineering and Springer-Verlag Berlin Heidelberg 2011