Neurocardiological differences between musicians and control subjects
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Exercise training is beneficial in health and disease. Part of the training effect materialises in the brainstem due to the exercise-associated somatosensory nerve traffic. Because active music making also involves somatosensory nerve traffic, we hypothesised that this will have training effects resembling those of physical exercise.
We compared two groups of healthy, young subjects between 18 and 30 years: 25 music students (13/12 male/female, group M) and 28 controls (12/16 male/female, group C), peers, who were non-musicians. Measurement sessions to determine resting heart rate, resting blood pressure and baroreflex sensitivity (BRS) were held during morning hours.
Groups M and C did not differ significantly in age (21.4 ± 3.0 vs 21.2 ± 3.1 years), height (1.79 ± 0.11 vs 1.77 ± 0.10 m), weight (68.0 ± 9.1 vs 66.8 ± 10.4 kg), body mass index (21.2 ± 2.5 vs 21.3 ± 2.4 kg∙m−2) and physical exercise volume (39.3 ± 38.8 vs 36.6 ± 23.6 metabolic equivalent hours/week). Group M practised music daily for 1.8 ± 0.7 h. In group M heart rate (65.1 ± 10.6 vs 68.8 ± 8.3 beats/min, trend P =0.08), systolic blood pressure (114.2 ± 8.7 vs 120.3 ± 10.0 mmHg, P = 0.01), diastolic blood pressure (65.0 ± 6.1 vs 71.0 ± 6.2 mmHg, P < 0.01) and mean blood pressure (83.7 ± 6.4 vs 89.4 ± 7.1, P < 0.01) were lower than in group C. BRS in groups M and C was 12.9 ± 6.7 and 11.3 ± 5.8 ms/mmHg, respectively (P = 0.17).
The results of our study suggest that active music making has training effects resembling those of physical exercise training. Our study opens a new perspective, in which active music making, additionally to being an artistic activity, renders concrete health benefits for the musician.
- Pliquett RU, Fasshauer M, Bluher M, et al. Neurohumoral stimulation in type-2-diabetes as an emerging disease concept. Cardiovasc Diabetol. 2004;3:4. CrossRef
- Hsueh WA, Wyne K. Renin-Angiotensin-aldosterone system in diabetes and hypertension. J Clin Hypertens (Greenwich). 2011;13:224–37. CrossRef
- Mancia G, Bousquet P, Elghozi JL, et al. The sympathetic nervous system and the metabolic syndrome. J Hypertens. 2007;25:909–20. CrossRef
- Essick EE, Sam F. Cardiac hypertrophy and fibrosis in the metabolic syndrome: a role for aldosterone and the mineralocorticoid receptor. Int J Hypertens. 2011;2011:346985.
- Triposkiadis F, Karayannis G, Giamouzis G, et al. The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol. 2009;54:1747–62. CrossRef
- Hein S, Arnon E, Kostin S, et al. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms. Circulation. 2003;107:984–91. CrossRef
- Izzo Jr JL, Gradman AH. Mechanisms and management of hypertensive heart disease: from left ventricular hypertrophy to heart failure. Med Clin North Am. 2004;88:1257–71. CrossRef
- Frenneaux MP. Autonomic changes in patients with heart failure and in post-myocardial infarction patients. Heart. 2004;90:1248–55. CrossRef
- Gademan MG, Swenne CA, Verwey HF, et al. Effect of exercise training on autonomic derangement and neurohumoral activation in chronic heart failure. J Card Fail. 2007;13:294–303. CrossRef
- Mueller PJ. Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Clin Exp Pharmacol Physiol. 2007;34:377–84. CrossRef
- Michelini LC, Stern JE. Exercise-induced neuronal plasticity in central autonomic networks: role in cardiovascular control. Exp Physiol. 2009;94:947–60. CrossRef
- Andersson S, Lundeberg T. Acupuncture–from empiricism to science: functional background to acupuncture effects in pain and disease. Med Hypotheses. 1995;45:271–81. CrossRef
- Thoren P, Floras JS, Hoffmann P, et al. Endorphins and exercise: physiological mechanisms and clinical implications. Med Sci Sports Exerc. 1990;22:417–28.
- Kaada B, Vik-mo H, Rosland G, et al. Transcutaneous nerve stimulation in patients with coronary arterial disease: haemodynamic and biochemical effects. Eur Heart J. 1990;11:447–53.
- Lee HS, Kim JY. Effects of acupuncture on blood pressure and plasma renin activity in two-kidney one clip Goldblatt hypertensive rats. Am J Chin Med. 1994;22:215–9. CrossRef
- Maeda M, Kachi H, Ichihashi N, et al. The effect of electrical acupuncture-stimulation therapy using thermography and plasma endothelin (ET-1) levels in patients with progressive systemic sclerosis (PSS). J Dermatol Sci. 1998;17:151–5. CrossRef
- Zhang S, Ye X, Shan Q, et al. Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. J Tradit Chin Med. 1999;19:39–43.
- Loaiza LA, Yamaguchi S, Ito M, et al. Electro-acupuncture stimulation to muscle afferents in anesthetized rats modulates the blood flow to the knee joint through autonomic reflexes and nitric oxide. Auton Neurosci. 2002;97:103–9. CrossRef
- Kaada B, Flatheim E, Woie L. Low-frequency transcutaneous nerve stimulation in mild/moderate hypertension. Clin Physiol. 1991;11:161–8. CrossRef
- Gademan MGJ, Sun Y, Han L, et al. Rehabilitation: periodic somatosensory stimulation increases arterial baroreflex sensitivity in chronic heart failure patients. Int J Cardiol. 2011;152:237–41. CrossRef
- Frederiks J, Swenne CA, Ghafoerkhan A, et al. Rhythmic sensory stimulation improves fitness by conditioning the autonomic nervous system. Neth Heart J. 2002;10:43–7.
- Ainsworth BE, Haskell WL, Herrmann SD, et al. 2011 Compendium of Physical Activities: a second update of codes and MET values. Med Sci Sports Exerc. 2011;43:1575–81. CrossRef
- Taylor CE, Atkinson G, Willie CK, et al. Diurnal variation in the mechanical and neural components of the baroreflex. Hypertension. 2011;58:51–6. CrossRef
- Gademan MG, Van Bommel RJ, Ypenburg C, et al. Biventricular pacing in chronic heart failure acutely facilitates the arterial baroreflex. Am J Physiol Heart Circ Physiol. 2008;295:H755–60. CrossRef
- Frederiks J, Swenne CA, Ten Voorde BJ, et al. The importance of high-frequency paced breathing in spectral baroreflex sensitivity assessment. J Hypertens. 2000;18:1635–44. CrossRef
- Swenne CA, Frederiks J, Fischer PH, et al. Noninvasive baroreflex sensitivity assessment in geriatric patients: feasibility, and role of the coherence criterion. Comput Cardiol. 2000;27:45–8.
- Van de Vooren H, Gademan MGJ, Haest JCW, et al. Non-invasive baroreflex sensitivity assessment in heart failure patients with frequent episodes of non-sinus rhythm. Comput Cardiol. 2006;33:637–40.
- Tanaka M, Sato M, Umehara S, et al. Influence of menstrual cycle on baroreflex control of heart rate: comparison with male volunteers. Am J Physiol Regul Integr Comp Physiol. 2003;285:R1091–7.
- Cervellin G, Lippi G. From music-beat to heart-beat: a journey in the complex interactions between music, brain and heart. Eur J Intern Med. 2011;22:371–4. CrossRef
- Montinaro A. The musical brain: myth and science. World Neurosurg. 2010;73:442–53. CrossRef
- Trappe HJ. The effects of music on the cardiovascular system and cardiovascular health. Heart. 2010;96:1868–71. CrossRef
- Inesta C, Terrados N, Garcia D, et al. Heart rate in professional musicians. J Occup Med Toxicol. 2008;3:16. CrossRef
- Sunderman LF. A study of some physiological differences between musicians and non-musicians; blood-pressure. J Soc Psychol. 1946;23:205–15. CrossRef
- Valentine E, Evans C. The effects of solo singing, choral singing and swimming on mood and physiological indices. Br J Med Psychol. 2001;74:115–20. CrossRef
- Clift SM, Hancox G. The perceived benefits of singing: findings from preliminary surveys of a university college choral society. J R Soc Promot Health. 2001;121:248–56. CrossRef
- Schorr-Lesnick B, Teirstein AS, Brown LK, et al. Pulmonary function in singers and wind-instrument players. Chest. 1985;88:201–5. CrossRef
- Zanesco A, Antunes E. Effects of exercise training on the cardiovascular system: pharmacological approaches. Pharmacol Ther. 2007;114:307–17. CrossRef
- Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc. 2004;36:533–53. CrossRef
- Halliwill JR, Taylor JA, Hartwig TD, et al. Augmented baroreflex heart rate gain after moderate-intensity, dynamic exercise. Am J Physiol. 1996;270:R420–6.
- Tirosh A, Afek A, Rudich A, et al. Progression of normotensive adolescents to hypertensive adults: a study of 26,980 teenagers. Hypertension. 2010;56:203–9. CrossRef
- Bibbins-Domingo K, Pletcher MJ. Blood pressure matters, even during young adulthood. J Am Coll Cardiol. 2011;58:2404–5. CrossRef
- Gray L, Lee IM, Sesso HD, et al. Blood pressure in early adulthood, hypertension in middle age, and future cardiovascular disease mortality: HAHS (Harvard Alumni Health Study). J Am Coll Cardiol. 2011;58:2396–403. CrossRef
- Neurocardiological differences between musicians and control subjects
Netherlands Heart Journal
Volume 21, Issue 4 , pp 183-188
- Cover Date
- Print ISSN
- Online ISSN
- Bohn Stafleu van Loghum
- Additional Links
- Exercise training
- Heart rate
- Blood pressure
- Author Affiliations
- 1. Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300 RC, Leiden, the Netherlands
- 2. Department of Public Health, Academic Medical Centre, Amsterdam, the Netherlands
- 3. Academy for Creative and Performing Arts, Faculty of Humanities, Leiden University, Leiden, the Netherlands
- 4. Pre-university College, Leiden University, Leiden, the Netherlands