Netherlands Heart Journal

, Volume 20, Issue 10, pp 410–418

CT fractional flow reserve: the next level in non-invasive cardiac imaging

  • M. F. L. Meijs
  • M. J. Cramer
  • H. El Aidi
  • P. A. Doevendans
Review Article

DOI: 10.1007/s12471-012-0306-6

Cite this article as:
Meijs, M.F.L., Cramer, M.J., El Aidi, H. et al. Neth Heart J (2012) 20: 410. doi:10.1007/s12471-012-0306-6

Abstract

The haemodynamic effect of a coronary artery stenosis is a better predictor of prognosis than anatomical lumen obstruction. Until recently, no individual non-invasive test could provide both accurate coronary anatomy and lesion-specific myocardial ischaemia. However, computer tomography (CT) fractional flow reserve, which can be calculated from a standard CT coronary angiogram, was recently demonstrated to accurately detect and rule out the haemodynamic significance of individual coronary artery stenoses.

Keywords

CT coronary angiographyFractional flow reserve (FFR)Non-invasive cardiac imagingSingle photon emission computed tomography (SPECT)Positron emission tomography (PET)Myocardial perfusion imaging

Copyright information

© Springer Media / Bohn Stafleu van Loghum 2012

Authors and Affiliations

  • M. F. L. Meijs
    • 1
  • M. J. Cramer
    • 1
  • H. El Aidi
    • 1
  • P. A. Doevendans
    • 1
  1. 1.Department of CardiologyUniversity Medical Centre UtrechtUtrechtthe Netherlands