Intracoronary Optical Coherence Tomography: Insights from Clinical Research—What Do We Need to Learn?

  • Maria D. Radu
  • Henning Kelbæk
  • Erik Jørgensen
  • Steffen Helqvist
  • Bettina Løjmand
  • Thomas Engstrøm
  • Kari I. Saunamäki
Intravascular Imaging (E Regar and U Landmesser, Section Editors)

DOI: 10.1007/s12410-014-9286-9

Cite this article as:
Radu, M.D., Kelbæk, H., Jørgensen, E. et al. Curr Cardiovasc Imaging Rep (2014) 7: 9286. doi:10.1007/s12410-014-9286-9
Part of the following topical collections:
  1. Topical Collection on Intravascular Imaging

Abstract

Optical coherence tomography (OCT) is a high-resolution technology for imaging of biological tissues that has shown tremendous potential for intracoronary use. Based on near-infrared light rather than ultrasound, catheter-based OCT provides cross-sectional images of the vessel wall and related devices in a histology-like manner. At present, OCT is primarily being used in research to better characterize and understand the pathophysiology of vulnerable plaques and to study the acute and long-term effects of coronary stent implantation. The present review provides the interventional cardiologist with a summary of the clinical research involving OCT, with an emphasis on specific challenges and how these may be overcome to promote a shift from the mainly research application of this technology, to a wider adoption in clinical practice.

Keywords

Optical coherence tomography Clinical research Plaque characterization Thin-cap fibroatheroma OCT-guided stent implantation Stent strut apposition Stent strut coverage Stent edge dissection Artefacts 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Maria D. Radu
    • 1
  • Henning Kelbæk
    • 1
  • Erik Jørgensen
    • 1
  • Steffen Helqvist
    • 1
  • Bettina Løjmand
    • 1
  • Thomas Engstrøm
    • 1
  • Kari I. Saunamäki
    • 1
  1. 1.Department of Cardiology, Section 2013The Heart Center, RigshospitaletCopenhagenDenmark