Current Cardiovascular Imaging Reports

, 7:9279

High Risk Plaque Features on Coronary CT Angiography

Authors

  • Andrea Bartykowszki
    • MTA-SE Lendület Cardiovascular Imaging Research GroupHeart and Vascular Center, Semmelweis University
  • Csilla Celeng
    • MTA-SE Lendület Cardiovascular Imaging Research GroupHeart and Vascular Center, Semmelweis University
  • Mihály Károlyi
    • MTA-SE Lendület Cardiovascular Imaging Research GroupHeart and Vascular Center, Semmelweis University
    • MTA-SE Lendület Cardiovascular Imaging Research GroupHeart and Vascular Center, Semmelweis University
Cardiac Computed Tomography (S Achenbach and T Villines, Section Editor)

DOI: 10.1007/s12410-014-9279-8

Cite this article as:
Bartykowszki, A., Celeng, C., Károlyi, M. et al. Curr Cardiovasc Imaging Rep (2014) 7: 9279. doi:10.1007/s12410-014-9279-8
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Part of the following topical collections:
  1. Topical Collection on Cardiac Computed Tomography

Abstract

Coronary computed tomography angiography (CCTA) is a non-invasive imaging technique that can detect, characterize and quantify coronary atherosclerotic plaques in routine clinical settings. The distinct morphological features of vulnerable plaques and stable lesions provide an opportunity for CCTA to identify high-risk plaque features and guide stratified therapeutic interventions. Morphological plaque characteristics, such as large plaque volume, positive remodelling, low CT attenuation, spotty calcification and the napkin-ring sign have been linked to elevated risk of acute coronary syndrome. Recent advances in computational fluid dynamics enabled functional plaque assessment through endothelial shear stress and lesion specific fractional flow reserve calculation. The comprehensive, morphological and functional plaque assessment may improve the identification of vulnerable coronary lesions.

Keywords

Coronary CT angiographyCoronary atherosclerosisVulnerable plaqueHigh plaque features

Copyright information

© Springer Science+Business Media New York 2014