Current Cardiovascular Imaging Reports

, Volume 5, Issue 5, pp 375–382

Imaging of Myocardial Perfusion and Late Enhancement

Cardiac Computed Tomography (TC Villines and S Achenbach, Section Editors)

DOI: 10.1007/s12410-012-9148-2

Cite this article as:
Blankstein, R. Curr Cardiovasc Imaging Rep (2012) 5: 375. doi:10.1007/s12410-012-9148-2


While coronary computed tomography angiography offers a noninvasive method to identify the presence or absence of coronary artery disease, the functional significance of anatomical lesions identified by this technique is often unknown. As a result, some patients may require further testing to assess for ischemia in order to help guide the need for further interventions. Recently, it has been recognized that cardiac CT is able to visualize rest and stress myocardial perfusion, thus enabling the possibility of evaluating the anatomical burden and physiological significance of coronary artery disease in a single exam. This article will provide an overview of CT perfusion and review the most recent developments relating to this new technique. The potential use of late enhancement imaging will also be discussed. Finally, an overview of the key research questions in this field will be presented followed by a discussion regarding the future direction of CT perfusion imaging.


Coronary artery diseaseIschemiaMyocardial perfusion imagingComputed tomographyMyocardial infarction

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Noninvasive Cardiovascular Imaging Program, Cardiovascular Division and Department of Radiology, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA