, Volume 3, Issue 6, pp 355-365
Date: 22 Sep 2010

Coronary CT Angiography for the Detection of Obstructive Coronary Artery Disease

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Contemporary CT scanners offer high temporal and spatial resolution, permitting visualization of the rapidly moving heart and coronary arteries. The imaging of coronary artery lumen and detection of obstructive coronary artery disease is feasible with 64-detector-row and higher generation CT scanners. The diagnostic accuracy of coronary CT angiography as compared to invasive coronary angiography is good (sensitivity of 85%–100%, specificity of 85%–99%). The major strength of coronary CT angiography is the high negative predictive value (96% to 99%) that permits excluding significant coronary artery stenosis with high accuracy, when optimal image quality is achieved. Therefore, coronary CT angiography is an appropriate diagnostic test for a selected patient population with a low to intermediate probability of coronary artery disease.