, Volume 21, Issue 2, pp 245-247
Date: 07 Feb 2014

The importance of heart rate response during myocardial perfusion imaging

This is an excerpt from the content

Myocardial perfusion imaging with single photon emission computed tomography (SPECT) is an established technique for the diagnosis of suspected coronary artery disease (CAD). Clinically even more important is the use of SPECT perfusion imaging for prognosis and risk stratification. Important parameters have been derived from SPECT imaging including the extent of scar tissue and the extent and severity of ischemia.1 In addition, various other prognostic variables have been identified, such as transient ischemic dilatation of the left ventricle (LV), and functional LV parameters including the LV ejection fraction (LVEF, at rest and stress) and LV volumes. Particularly, Sharir et al2 evaluated 1,680 patients and demonstrated that the post-stress LVEF provided incremental prognostic value over perfusion abnormalities. The incremental value of adding LVEF was most pronounced in patients with mild-moderate abnormal perfusion, where the annual cardiac death rate was 0.96% when the LVEF was ≥4 ...

See related article, doi:10.1007/s12350-013-9820-1.