Journal of Nuclear Cardiology

, Volume 20, Issue 2, pp 289–296

CT imaging of myocardial perfusion: Possibilities and perspectives

Review Article

DOI: 10.1007/s12350-013-9681-7

Cite this article as:
Becker, A. & Becker, C. J. Nucl. Cardiol. (2013) 20: 289. doi:10.1007/s12350-013-9681-7


Functional imaging in patients with suspected or known coronary artery disease (CAD) is crucial for the identification of patients who could benefit from coronary revascularization. Several studies demonstrated the high diagnostic accuracy of Single-photon-emission computed tomography myocardial perfusion imaging, stress perfusion magnetic resonance imaging, and of invasive FFR measurements for the detection of hemodynamic relevant stenosis. Cardiac computed tomography (CT) used to be limited to coronary angiography (CTA); current guidelines recommend CTA only for the exclusion of CAD. Technological advances now offer the possibility to assess myocardial perfusion by computed tomography (CT-MPI). Though different acquisition protocols and post-processing algorithms still have to be evaluated, initial clinical studies could already show a diagnostic accuracy comparable to the established imaging modalities. Thus, cardiac CT may offer a combined approach of anatomical and functional imaging. Beside the need for further studies, especially on the prognostic value of CT-MPI to stratify future cardiovascular events, the comparatively high radiation exposure and additional administration of contrast agent has to be taken in account.


Computed tomography (CT)coronary artery diseaseexercise: stress testingischemiamyocardial

Copyright information

© American Society of Nuclear Cardiology 2013

Authors and Affiliations

  1. 1.Department of CardiologyLudwig-Maximilians-University MunichMunichGermany
  2. 2.Department of Clinical RadiologyLudwig-Maximilians-University MunichMunichGermany