, Volume 19, Issue 6, pp 1106-1109
Date: 15 Sep 2012

Stress first myocardial perfusion imaging: Is it time to put to rest the “Rest First” strategy for most patients?

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While myocardial perfusion imaging (MPI) remains the most validated and extensively utilized modality in the evaluation and prognostication of coronary artery disease (CAD), it has come under unprecedented scrutiny in the past few years both due to the expansive growth of cardiac imaging1 and increasing concerns of patient radiation exposure over their lifetime. In one study, nuclear cardiac imaging was reported to be contributing up to 22% of radiation exposure amongst all imaging.2

Over the past few years, major cardiac societies such as the American College of Cardiology/American Heart Association in collaboration with many other imaging societies have taken proactive steps to guide the use of cardiac imaging. Appropriate use criteria for nuclear cardiology, echocardiography, CT/MRI, and most recently, cardiac catheterization and percutaneous coronary interventions have been published to ensure that clinicians in most instances are “doing the right test for the right patient at the r

Research grant support/speakers bureau: Astellas Pharma US Inc (KA), Lantheus Medical Imaging.
See related article, doi:10.1007/s12350-012-9606-x.