, Volume 17, Issue 3, pp 350-353
Date: 09 Apr 2010

Are people with normal radionuclide perfusion imaging studies better-off if they are obese?

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Obesity has reached global epidemic proportions. According to World Health Organization (WHO) statistics, there are more than 1 billion overweight (body mass index, i.e., BMI, > 25 kg/m2) adults, with at least 300 million of them clinically obese (BMI > 30 kg/m2).1 In the United States (US), there has been an alarming increase in the prevalence of obesity, with rates increasing by nearly 50% among adults between 1980 and 2000. The age-adjusted prevalence of obesity is about 33%, translating into more than 70 million US adults.2-4

Obesity is a major contributor to the global burden of chronic disease, and is customarily considered to increase cardiovascular risk. While not specifically a Framingham risk factor, obesity is associated with conventional cardiac risk factors such as diabetes mellitus, hypertension, and hyperlipidemia. Nevertheless, obesity has by itself been shown to increase risk by inducing a pro-inflammatory, pro-thrombotic, and atherogenic state that leads to cardiovascu ...

See related article on doi:10.1007/s12350-010-9214-6