Clinical Journal of Gastroenterology

, Volume 6, Issue 1, pp 50–54

Adult-onset diffuse nesidioblastosis causing hypoglycemia

Authors

    • Department of GastroenterologyNikko Memorial Hospital
    • Digestive Disease CenterShowa University Northern Yokohama Hospital
  • Kazunori Yokoyama
    • Department of GastroenterologyNikko Memorial Hospital
  • Kenichi Takeda
    • Department of GastroenterologyNikko Memorial Hospital
    • Digestive Disease CenterShowa University Northern Yokohama Hospital
  • Jyouji Takada
    • Department of SurgeryNikko Memorial Hospital
  • Hiromi Hamada
    • Department of SurgeryNikko Memorial Hospital
  • Yasunori Hujioka
    • Department of PathologyNikko Memorial Hospital
  • Shin-ei Kudo
    • Digestive Disease CenterShowa University Northern Yokohama Hospital
Case Report

DOI: 10.1007/s12328-012-0335-0

Cite this article as:
Maeda, Y., Yokoyama, K., Takeda, K. et al. Clin J Gastroenterol (2013) 6: 50. doi:10.1007/s12328-012-0335-0
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Abstract

We report the case of a 32-year-old male with adult-onset diffuse nesidioblastosis causing hypoglycemia. Under the tentative diagnosis of insulinoma, localization procedures were carried out but no tumor was found. The presence of an insulinoma in the tail of the pancreas was suggested by selective intra-arterial calcium stimulation with hepatic venous sampling (ASVS). A distal pancreatectomy was performed under the assumed diagnosis of insulinoma in the tail based upon the ASVS. Diffuse nesidioblastosis was diagnosed by histopathological evaluation. During the post-operative course, the patient’s glucose and insulin levels were well controlled and uneventful without any medications or insulin for 7 months.

Keywords

HypoglycemiaNesidioblastosisASVS

Copyright information

© Springer Japan 2012