Advances in Therapy

, Volume 26, Issue 7, pp 711–718

Dyslipidemia therapy update: the importance of full lipid profile assessment

  • I. B. A. Menown
  • G. Murtagh
  • V. Maher
  • M. T. Cooney
  • I. M. Graham
  • G. Tomkin
Review

DOI: 10.1007/s12325-009-0052-3

Cite this article as:
Menown, I.B.A., Murtagh, G., Maher, V. et al. Adv Therapy (2009) 26: 711. doi:10.1007/s12325-009-0052-3

Abstract

Lipid guidelines typically focus on total cholesterol ± low-density lipoprotein cholesterol levels with less emphasis on high-density lipoprotein cholesterol (HDL-C) or triglyceride assessment, thus potentially underestimating cardiovascular (CV) risk and the need for lifestyle or treatment optimization. In this article, we highlight how reliance on isolated total cholesterol assessment may miss prognostically relevant lipid abnormalities; we describe from the European Systematic COronary Risk Evaluation (SCORE) data set how incorporation of HDL-C may improve estimation of CV risk; and, finally, we critically evaluate the evidence base surrounding triglycerides and CV risk.

Keywords

cardiovascular risk cholesterol dyslipidemia high-density lipoprotein cholesterol triglycerides 

Copyright information

© Springer Healthcare Communications 2009

Authors and Affiliations

  • I. B. A. Menown
    • 1
  • G. Murtagh
    • 2
  • V. Maher
    • 2
  • M. T. Cooney
    • 2
  • I. M. Graham
    • 2
  • G. Tomkin
    • 3
  1. 1.Craigavon Cardiac Centre, CraigavonNorthern IrelandUK
  2. 2.Adelaide, Meath and National Children’s Hospital (AMNCH), TallaghtDublinIreland
  3. 3.Diabetes Institute of Ireland, Beacon Clinic, SandyfordDublinIreland