Cancer Microenvironment

, Volume 4, Issue 2, pp 209–217

Cancer-Immune Equilibrium: Questions Unanswered

Authors

Review Paper

DOI: 10.1007/s12307-011-0065-8

Cite this article as:
Bhatia, A. & Kumar, Y. Cancer Microenvironment (2011) 4: 209. doi:10.1007/s12307-011-0065-8

Abstract

Cancer-immune (CI) equilibrium constitutes an important component of the cancer immunoediting theory. It is defined as a period during which our immune system and cancer live in harmony in the body. The immune system, though not able to completely eliminate the cancer, doesn’t allow it to progress or metastasize further. Mechanisms of this phase are poorly understood because this phase is difficult to identify even by the most modern detection methods. Till now, the work done on the equilibrium phase of cancer, suggests promising improvements in cancer therapy if the disease could be withheld in this phase. However, there are many queries which remain to be addressed about this interesting yet unresolved phase of cancer immunity.

Keywords

ImmunoeditingEliminationImmune equilibriumEscapeMechanisms

Copyright information

© Springer Science+Business Media B.V. 2011