Chromosomal mosaicism for inversion of chromosome 3(p25, p26) in a case of idiopathic hypereosinophilic syndrome (IHES)

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Abstract

Cytogenetic analysis and molecular genetic studies help for diagnosis of IHES and differentiation between IHES and other hematologic disorders with eosinophilia. We want to present a case of IHES with chromosomal mosaicism for inversion of chromosome 3(p25, p26), who achieved complete remission after treatment with Imatinib and short course of prednisolone.