Indian Journal of Hematology and Blood Transfusion

, Volume 27, Issue 1, pp 35–38

A Case of HIV Infection with Thrombocytopenia: Assosiation of HIV, Thrombotic Thrombocytopenic Purpura and Brucellosis

Authors

    • Infectious Disease Department, Faculty of MedicineCukurova University
  • Ozgur Akin Oto
    • Internal Medicine DepartmentPrivate Care Hospital
  • Aslihan Candevir
    • Infectious Disease Department, Faculty of MedicineCukurova University
  • Ayse Seza Inal
    • Infectious Disease Department, Faculty of MedicineCukurova University
  • Yusuf Sirin
    • Internal Medicine Department, Faculty of MedicineCukurova University
Case Report

DOI: 10.1007/s12288-010-0049-8

Cite this article as:
Kurtaran, B., Oto, O.A., Candevir, A. et al. Indian J Hematol Blood Transfus (2011) 27: 35. doi:10.1007/s12288-010-0049-8

Abstract

To report a case of HIV infection presenting with thrombotic thrombocytopenic purpura (TTP) and brucellosis that responded well to plasmapheresis and anti-infective therapy. A 64-year-old woman with moderate confusion, fever and pancytopenia was admitted. HIV infection history was taken from her family and she was not receiving antiretroviral therapy last one year. She had generalized purpuric skin lesions. Wright tube agglutination test was found positive with a 1:160 dilution and the patient was diagnosed as brucellosis. Detailed literature search showed brucellosis as a possible cause of TTP. Patient was treated by plasma exchange/fresh frozen plasma and antimicrobials and the response was excellent. Although brucellosis seems to explain the clinical picture of this patient, it is revealed that broad differential diagnosis is needed to reach uncommon diagnosis like TTP particularly in HIV infected patients.

Keywords

HIV Brucellosis Thrombotic thrombocytopenic purpura Plasma exchange

Copyright information

© Indian Society of Haematology & Transfusion Medicine 2011