Breast Cancer

, Volume 22, Issue 2, pp 206–209

Metastatic breast carcinoma of the abdominal wall muscle: a case report

  • Akiko Ogiya
  • Kaoru Takahashi
  • Mutsumi Sato
  • Yoshiko Kubo
  • Noriko Nishikawa
  • Mariko Kikutani
  • Yukiko Tadokoro
  • Kumiko Tanaka
  • Takayoshi Uematsu
  • Junichiro Watanabe
  • Masako Kasami
  • Seiji Yamasaki
Case Report

DOI: 10.1007/s12282-012-0352-3

Cite this article as:
Ogiya, A., Takahashi, K., Sato, M. et al. Breast Cancer (2015) 22: 206. doi:10.1007/s12282-012-0352-3

Abstract

Metastasis from breast carcinoma is an uncommon occurrence in skeletal muscle, compared to local invasion into muscle from direct tumor spread. A 49-year-old woman was referred to our hospital with an 8.5-cm mass in the right breast. Core needle biopsy revealed metaplastic carcinoma with squamous metaplasia. The mass was rapidly growing and metaplastic, so mastectomy with dissection of axillary lymph nodes was performed. Pathological examination showed metaplastic carcinoma, histological grade 3, triple negative, and a MIB-1 labeling index of 80%. Six months postoperatively, during adjuvant chemotherapy treatment, she reported numbness and pain in the right lateral thigh and a mass in the right lower abdomen. Computed tomography revealed multiple lined masses in the abdominal wall and iliac muscle. Core needle biopsy showed metastatic breast carcinoma. Radio- and chemotherapy were administered, but the mass in the muscle became enlarged. To control her pain, a combined treatment with morphine, fentanyl, ketamine, antiepilepsy drug, and NSAIDs was administered. Liver metastasis appeared 9 months (15 months postoperatively) after recognition of muscle metastasis, and the patient died 16 months postoperatively. Skeletal muscle metastasis is uncommon, and therapeutic intervention is mainly palliative. The most common symptom of skeletal muscle metastasis is pain; thus, pain control is a pivotal goal of treatment.

Keywords

Breast cancerSkeletal muscleMetastasis

Copyright information

© The Japanese Breast Cancer Society 2012

Authors and Affiliations

  • Akiko Ogiya
    • 1
  • Kaoru Takahashi
    • 1
  • Mutsumi Sato
    • 1
  • Yoshiko Kubo
    • 1
  • Noriko Nishikawa
    • 1
  • Mariko Kikutani
    • 1
  • Yukiko Tadokoro
    • 1
  • Kumiko Tanaka
    • 1
  • Takayoshi Uematsu
    • 2
  • Junichiro Watanabe
    • 3
  • Masako Kasami
    • 4
  • Seiji Yamasaki
    • 5
  1. 1.Department of Breast SurgeryShizuoka Cancer Center HospitalShizuokaJapan
  2. 2.Department of Breast Imaging and Breast InterventionShizuoka Cancer Center HospitalShizuokaJapan
  3. 3.Department of Medical OncologyShizuoka Cancer Center HospitalShizuokaJapan
  4. 4.Department of PathologyShizuoka Cancer Center HospitalShizuokaJapan
  5. 5.Department of Multidisciplinary Therapy for Breast CancerShizuoka Cancer Center HospitalShizuokaJapan